Flow Diversion for Middle Cerebral Artery Aneurysms: An International Cohort Study.


Journal

Neurosurgery
ISSN: 1524-4040
Titre abrégé: Neurosurgery
Pays: United States
ID NLM: 7802914

Informations de publication

Date de publication:
18 11 2021
Historique:
received: 09 01 2021
accepted: 06 08 2021
pubmed: 9 10 2021
medline: 24 3 2022
entrez: 8 10 2021
Statut: ppublish

Résumé

Open surgery has traditionally been preferred for the management of bifurcation middle cerebral artery (MCA) aneurysms. Flow diverting stents present a novel endovascular strategy for aneurysm treatment. To add to the limited literature describing the outcomes and complications in the use of flow diverters for the treatment of these complex aneurysms. This is a multicenter retrospective review of MCA bifurcation aneurysms undergoing flow diversion. We assessed post-treatment radiological outcomes and both thromboembolic and hemorrhagic complications. We reviewed the outcomes of 54 aneurysms treated with flow diversion. Four (7.4%) of the aneurysms had a history of rupture (3 remote and 1 acute). Fourteen (25.9%) of the aneurysms already underwent either open surgery or coiling prior to flow diversion. A total of 36 out of the 45 aneurysms (80%) with available follow-up data had adequate aneurysm occlusion with a median follow-up time of 12 mo. There were no hemorrhagic complications but 16.7% (9/54) had thromboembolic complications. Flow diverting stents may be a viable option for the endovascular treatment of complex bifurcation MCA aneurysms. However, compared to published series on the open surgical treatment of this subset of aneurysms, flow diversion has inferior outcomes and are associated with a higher rate of complications.

Sections du résumé

BACKGROUND
Open surgery has traditionally been preferred for the management of bifurcation middle cerebral artery (MCA) aneurysms. Flow diverting stents present a novel endovascular strategy for aneurysm treatment.
OBJECTIVE
To add to the limited literature describing the outcomes and complications in the use of flow diverters for the treatment of these complex aneurysms.
METHODS
This is a multicenter retrospective review of MCA bifurcation aneurysms undergoing flow diversion. We assessed post-treatment radiological outcomes and both thromboembolic and hemorrhagic complications.
RESULTS
We reviewed the outcomes of 54 aneurysms treated with flow diversion. Four (7.4%) of the aneurysms had a history of rupture (3 remote and 1 acute). Fourteen (25.9%) of the aneurysms already underwent either open surgery or coiling prior to flow diversion. A total of 36 out of the 45 aneurysms (80%) with available follow-up data had adequate aneurysm occlusion with a median follow-up time of 12 mo. There were no hemorrhagic complications but 16.7% (9/54) had thromboembolic complications.
CONCLUSION
Flow diverting stents may be a viable option for the endovascular treatment of complex bifurcation MCA aneurysms. However, compared to published series on the open surgical treatment of this subset of aneurysms, flow diversion has inferior outcomes and are associated with a higher rate of complications.

Identifiants

pubmed: 34624100
pii: 6384797
doi: 10.1093/neuros/nyab365
doi:

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

1112-1121

Commentaires et corrections

Type : CommentIn
Type : CommentIn

Informations de copyright

© Congress of Neurological Surgeons 2021.

Auteurs

Jose Danilo Bengzon Diestro (JDB)

Division of Diagnostic & Therapeutic Neuroradiology, Department of Radiology, St. Michael's Hospital (Unity Health), University of Toronto, Toronto, Ontario, Canada.
Département de Radiologie, Radio-oncologie et Médecine Nucléaire, Centre Hospitalier de l'Université de Montréal, Université de Montréal, Montréal, Québec, Canada.

Nimer Adeeb (N)

Departments of Neurosurgery & Interventional Neuroradiology, LSU Shreveport School of Medicine, Shreveport, Louisiana, USA.

Mahmoud Dibas (M)

Departments of Neurosurgery & Interventional Neuroradiology, LSU Shreveport School of Medicine, Shreveport, Louisiana, USA.

William Boisseau (W)

Département de Radiologie, Radio-oncologie et Médecine Nucléaire, Centre Hospitalier de l'Université de Montréal, Université de Montréal, Montréal, Québec, Canada.

Pablo Harker (P)

Neuroendovascular Program, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Department of Neurology, University of Cincinnati, Cincinnati, Ohio, USA.

Waleed Brinjikji (W)

Departments of Radiology & Neurological Surgery, Mayo Clinic, Rochester, Minnesota, USA.

Sishi Xiang (S)

Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.

Evan Joyce (E)

Department of Neurosurgery, University of Utah, Salt Lake City, Utah, USA.

Maksim Shapiro (M)

Departments of Radiology and Neurosurgery, NYU Langone Health, New York, New York, USA.

Eytan Raz (E)

Departments of Radiology and Neurosurgery, NYU Langone Health, New York, New York, USA.

Carmen Parra-Farinas (C)

Division of Diagnostic & Therapeutic Neuroradiology, Department of Radiology, St. Michael's Hospital (Unity Health), University of Toronto, Toronto, Ontario, Canada.

Gwynedd Pickett (G)

Department of Neurosurgery, Queen Elizabeth II Health Science Centre, Dalhousie Medical School, Halifax, Nova Scotia, Canada.

Naif M Alotaibi (NM)

Neuroendovascular Program, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Department of Neurosurgery, National Neuroscience Institute, King Fahad Medical City, Riyadh, Saudi Arabia.

Robert W Regenhardt (RW)

Neuroendovascular Program, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Joshua D Bernstock (JD)

Neuroendovascular Program, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Julian Spears (J)

Division of Diagnostic & Therapeutic Neuroradiology, Department of Radiology, St. Michael's Hospital (Unity Health), University of Toronto, Toronto, Ontario, Canada.

Christoph J Griessenauer (CJ)

Department of Neurosurgery, Geisinger, Danville, Pennsylvania, USA.
Research Institute of Neurointervention, Paracelsus Medical University, Salzburg, Austria.
Department of Neurosurgery, Christian Doppler Klinik, Paracelsus Medical University, Salzburg, Austria.

Jan-Karl Burkhardt (JK)

Department of Neurosurgery, University of Pennsylvania, Penn Medicine, Philadelphia, Pennsylvania, USA.

Muhammad U Hafeez (MU)

Department of Neurosurgery, Baylor College of Medicine, Houston, Texas, USA.

Peter Kan (P)

Department of Neurosurgery, University of Texas Medical Branch, Houston, Texas, USA.

Ramesh Grandhi (R)

Department of Neurosurgery, University of Utah, Salt Lake City, Utah, USA.

Philipp Taussky (P)

Department of Neurosurgery, University of Utah, Salt Lake City, Utah, USA.

Erez Nossek (E)

Departments of Radiology and Neurosurgery, NYU Langone Health, New York, New York, USA.

Tao Hong (T)

Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.

Hongqi Zhang (H)

Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.

Lorenzo Rinaldo (L)

Departments of Radiology & Neurological Surgery, Mayo Clinic, Rochester, Minnesota, USA.

Giuseppe Lanzino (G)

Departments of Radiology & Neurological Surgery, Mayo Clinic, Rochester, Minnesota, USA.

Christopher J Stapleton (CJ)

Neuroendovascular Program, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

James D Rabinov (JD)

Neuroendovascular Program, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Aman B Patel (AB)

Neuroendovascular Program, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Thomas R Marotta (TR)

Division of Diagnostic & Therapeutic Neuroradiology, Department of Radiology, St. Michael's Hospital (Unity Health), University of Toronto, Toronto, Ontario, Canada.

Daniel Roy (D)

Département de Radiologie, Radio-oncologie et Médecine Nucléaire, Centre Hospitalier de l'Université de Montréal, Université de Montréal, Montréal, Québec, Canada.

Adam A Dmytriw (AA)

Division of Diagnostic & Therapeutic Neuroradiology, Department of Radiology, St. Michael's Hospital (Unity Health), University of Toronto, Toronto, Ontario, Canada.
Neuroendovascular Program, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH