Diattenuation and retardance signature of plasmonic gold nanorods in turbid media revealed by Mueller matrix polarimetry.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
08 10 2021
08 10 2021
Historique:
received:
14
06
2021
accepted:
15
09
2021
entrez:
9
10
2021
pubmed:
10
10
2021
medline:
10
10
2021
Statut:
epublish
Résumé
Plasmonic gold nanorods (GNRs) are finding increasing use in biomedicine due to their unique electromagnetic properties, optical contrast enhancement and biocompatibility; they also show promise as polarization contrast agents. However, quantification of their polarization-enhancing properties within heterogeneous turbid media remains challenging. We report on polarization response in controlled tissue phantoms consisting of dielectric microsphere scatterers with varying admixtures of GRNs. Experimental Mueller matrix measurements and polarization sensitive Monte-Carlo simulations show excellent agreement. Despite the GNRs' 3D random orientation and distribution in the strong multiply scattering background, significant linear diattenuation and retardance were observed. These exclusive measurable characteristics of GNRs suggest their potential uses as contrast enhancers for polarimetric assessment of turbid biological tissue.
Identifiants
pubmed: 34625628
doi: 10.1038/s41598-021-99430-6
pii: 10.1038/s41598-021-99430-6
pmc: PMC8501131
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
20017Subventions
Organisme : CIHR
ID : CIHR, PJT-156110
Pays : Canada
Informations de copyright
© 2021. The Author(s).
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