Impact of Body Mass Index and Discomfort on Upper Airway Stimulation: ADHERE Registry 2020 Update.
Aged
Body Mass Index
Electric Stimulation Therapy
/ adverse effects
Female
Humans
Implantable Neurostimulators
/ adverse effects
Male
Middle Aged
Patient Compliance
/ statistics & numerical data
Prospective Studies
Registries
/ statistics & numerical data
Severity of Illness Index
Sleep Apnea, Obstructive
/ diagnosis
Treatment Outcome
Hypoglossal nerve stimulation
neurostimulation
sleep apnea
sleep surgery
upper airway stimulation
Journal
The Laryngoscope
ISSN: 1531-4995
Titre abrégé: Laryngoscope
Pays: United States
ID NLM: 8607378
Informations de publication
Date de publication:
11 2021
11 2021
Historique:
revised:
06
06
2021
received:
12
10
2020
accepted:
06
07
2021
entrez:
9
10
2021
pubmed:
10
10
2021
medline:
25
11
2021
Statut:
ppublish
Résumé
To provide the ADHERE registry Upper Airway Stimulation (UAS) outcomes update, including analyses grouped by body mass index (BMI) and therapy discomfort. Prospective observational study. ADHERE captures UAS outcomes including apnea-hypopnea index (AHI), Epworth sleepiness scale (ESS), therapy usage, patient satisfaction, clinician assessment, and safety over a 1-year period. BMI ≤32 kg/m One thousand eight hundred forty-nine patients enrolled in ADHERE, 1,019 reached final visit, 843 completed the visit. Significant changes in AHI (-20.9, P < .0001) and ESS (- 4.4, P < .0001) were demonstrated. Mean therapy usage was 5.6 ± 2.2 hr/day. Significant therapy use difference was present in patients with reported discomfort versus no discomfort (4.9 ± 2.5 vs. 5.7 ± 2.1 hr/day, P = .01). Patients with discomfort had higher final visit mean AHI versus without discomfort (18.9 ± 18.5 vs. 13.5 ± 13.7 events/hr, P = .01). Changes in AHI and ESS were not significantly different. Serious adverse events reported in 2.3% of patients. Device revision rate was 1.9%. Surgical success was less likely in BMI Data from ADHERE demonstrate high efficacy rates for UAS. Although surgical response rate differs between BMI 4 Laryngoscope, 131:2616-2624, 2021.
Types de publication
Journal Article
Multicenter Study
Observational Study
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2616-2624Subventions
Organisme : Inspire Medical
Informations de copyright
© 2021 The American Laryngological, Rhinological and Otological Society, Inc.
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