The impact of social distancing during the COVID-19 pandemic on rates of pediatric idiopathic intussusception.
COVID-19
Children
Hypertrophic pyloric stenosis
Intussusception
Pathogenesis
Ultrasound
Journal
Pediatric radiology
ISSN: 1432-1998
Titre abrégé: Pediatr Radiol
Pays: Germany
ID NLM: 0365332
Informations de publication
Date de publication:
03 2022
03 2022
Historique:
received:
09
06
2021
accepted:
16
09
2021
revised:
23
08
2021
pubmed:
10
10
2021
medline:
25
2
2022
entrez:
9
10
2021
Statut:
ppublish
Résumé
The causes of idiopathic ileocolic intussusception are unknown, with infection as the most likely culprit. Recently, social distancing measures were implemented during the coronavirus disease 2019 (COVID-19) pandemic to decrease transmissible infectious diseases, creating an opportune setting to study the role of infection on the pathogenesis of intussusception on a population level. To investigate the impact of social distancing on intussusception. We retrospectively reviewed air contrast enemas and pylorus ultrasounds performed between March 2010 and March 2021 to identify cases of ileocolic intussusception and hypertrophic pyloric stenosis (HPS), using the latter as a negative control. The study time frame was divided into two periods: pre-pandemic (March 2010-February 2020) and pandemic (April 2020-March 2021). The number of cases that occurred in these two time periods were compared using the Poisson regression model. Of the 407 cases of idiopathic ileocolic intussusception identified, 396 occurred in the pre-pandemic time period (mean = 39.6 per 12-month period) and 11 occurred in the 12-month pandemic time period. The mean monthly number of intussusceptions showed a decline of 72% (95% confidence interval [CI] 49-85%) between the pre-pandemic and pandemic time periods (3.3 vs. 0.9 monthly cases; P < 0.001). In contrast, the mean monthly number of HPS did not differ significantly (P = 0.19). Social distancing-imposed to curb the spread of infection during the COVID-19 pandemic-resulted in a significant decline in ileocolic intussusception, lending strong support to the theory that infection is the dominant cause of intussusception.
Sections du résumé
BACKGROUND
The causes of idiopathic ileocolic intussusception are unknown, with infection as the most likely culprit. Recently, social distancing measures were implemented during the coronavirus disease 2019 (COVID-19) pandemic to decrease transmissible infectious diseases, creating an opportune setting to study the role of infection on the pathogenesis of intussusception on a population level.
OBJECTIVE
To investigate the impact of social distancing on intussusception.
MATERIALS AND METHODS
We retrospectively reviewed air contrast enemas and pylorus ultrasounds performed between March 2010 and March 2021 to identify cases of ileocolic intussusception and hypertrophic pyloric stenosis (HPS), using the latter as a negative control. The study time frame was divided into two periods: pre-pandemic (March 2010-February 2020) and pandemic (April 2020-March 2021). The number of cases that occurred in these two time periods were compared using the Poisson regression model.
RESULTS
Of the 407 cases of idiopathic ileocolic intussusception identified, 396 occurred in the pre-pandemic time period (mean = 39.6 per 12-month period) and 11 occurred in the 12-month pandemic time period. The mean monthly number of intussusceptions showed a decline of 72% (95% confidence interval [CI] 49-85%) between the pre-pandemic and pandemic time periods (3.3 vs. 0.9 monthly cases; P < 0.001). In contrast, the mean monthly number of HPS did not differ significantly (P = 0.19).
CONCLUSION
Social distancing-imposed to curb the spread of infection during the COVID-19 pandemic-resulted in a significant decline in ileocolic intussusception, lending strong support to the theory that infection is the dominant cause of intussusception.
Identifiants
pubmed: 34626197
doi: 10.1007/s00247-021-05211-8
pii: 10.1007/s00247-021-05211-8
pmc: PMC8501347
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
453-459Informations de copyright
© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
Références
Clin Infect Dis. 2021 Jul 1;73(1):e132-e140
pubmed: 32472687
Br J Surg. 1992 Sep;79(9):867-76
pubmed: 1422744
Pediatrics. 2007 Sep;120(3):473-80
pubmed: 17766518
Ital J Pediatr. 2021 Jan 29;47(1):21
pubmed: 33514391
Pediatr Radiol. 2002 Jan;32(1):74
pubmed: 11819068
Arch Pathol Lab Med. 2001 Nov;125(11):1486-8
pubmed: 11698009
Pediatr Infect Dis J. 1994 Jun;13(6):548-9
pubmed: 8078750
Pediatr Radiol. 1998 Dec;28(12):913-9
pubmed: 9880629
Pediatr Radiol. 2017 Oct;47(11):1471-1476
pubmed: 28578475
J Pediatr Gastroenterol Nutr. 1996 Jul;23(1):77-80
pubmed: 8811527
Pediatrics. 2020 Oct;146(4):
pubmed: 32879032
Klin Padiatr. 1998 Mar-Apr;210(2):61-4
pubmed: 9561958
AJR Am J Roentgenol. 1988 Jun;150(6):1367-70
pubmed: 3285655
MMWR Morb Mortal Wkly Rep. 1999 Nov 5;48(43):1007
pubmed: 10577495
J R Soc Med. 2005 Aug;98(8):368-9
pubmed: 16055906
Radiol Clin North Am. 1996 Jul;34(4):743-56
pubmed: 8677307
J Paediatr Child Health. 2020 Jul;56(7):1165
pubmed: 32725733
Dig Liver Dis. 2004 Aug;36(8):557
pubmed: 15334779
MMWR Recomm Rep. 2017 Aug 25;66(2):1-20
pubmed: 28841201
PLoS One. 2013 Jul 22;8(7):e68482
pubmed: 23894308
Glob Pediatr Health. 2021 May 8;8:2333794X211012978
pubmed: 34017904
Abdom Imaging. 2008 Jan-Feb;33(1):38-40
pubmed: 17828425
J Pediatr Gastroenterol Nutr. 2001 Sep;33(3):289, 300
pubmed: 11601434
J Pediatr. 2010 May;156(5):761-5
pubmed: 20138300
J Pediatr Gastroenterol Nutr. 1998 Sep;27(3):301-5
pubmed: 9740201
Clin Colon Rectal Surg. 2017 Feb;30(1):30-39
pubmed: 28144210
J Med Virol. 1978;2(3):265-69
pubmed: 212529
Emerg Radiol. 2020 Dec;27(6):761-764
pubmed: 33025218
Neonatal Netw. 2018 Jul;37(4):197-204
pubmed: 30567916
Pediatr Infect Dis J. 1998 Oct;17(10):893-8
pubmed: 9802631
Pediatr Radiol. 2020 May;50(5):664-672
pubmed: 32006065
Am J Dis Child. 1992 Nov;146(11):1331-3
pubmed: 1415074
N Engl J Med. 2001 Feb 22;344(8):564-72
pubmed: 11207352
Am J Dis Child. 1983 Aug;137(8):803-4
pubmed: 6869343
AJR Am J Roentgenol. 2015 Nov;205(5):W542-9
pubmed: 26496576
Radiographics. 1999 Mar-Apr;19(2):299-319
pubmed: 10194781
Pediatr Radiol. 2017 Aug;47(9):1101-1108
pubmed: 28779197
J Pediatr. 2006 Oct;149(4):452-60
pubmed: 17011313
J Pediatric Infect Dis Soc. 2020 Sep 17;9(4):504-506
pubmed: 32770243
J Med Virol. 1982;9(4):267-71
pubmed: 6286861
Pediatr Radiol. 2019 Jan;49(1):76-81
pubmed: 30232533
Radiographics. 2000 Sep-Oct;20(5):E1
pubmed: 10992040
J Pediatr Surg. 1992 Dec;27(12):1591-2
pubmed: 1469587
Pediatrics. 2020 Dec;146(6):
pubmed: 33144496
Am J Gastroenterol. 1994 Aug;89(8):1246-8
pubmed: 8053444