High pressure Raman investigation on trans-urocanic acid.
Cis-urocanic acid
High pressure
Isomerization
Polymerization
Raman
Trans-urocanic acid
Journal
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
ISSN: 1873-3557
Titre abrégé: Spectrochim Acta A Mol Biomol Spectrosc
Pays: England
ID NLM: 9602533
Informations de publication
Date de publication:
05 Feb 2022
05 Feb 2022
Historique:
received:
03
05
2021
revised:
27
08
2021
accepted:
22
09
2021
pubmed:
10
10
2021
medline:
24
11
2021
entrez:
9
10
2021
Statut:
ppublish
Résumé
Trans-urocanic acid (t-UCA) is an important epidermal UV protector predominantly found in human skin. Exposure of UV radiation triggers photoisomerization of t-UCA into its other conformer, cis-urocanic acid (cis-UCA), which has been shown to be a mediator of UV-induced immune-suppression leading to skin cancer. In this report, we present the investigation of molecular changes of t-UCA under high pressures by in-situ high pressure Raman spectroscopy. The study indicates onset of ring opening polymerization of t-UCA at pressure above 1.4 GPa. At pressures beyond 5 GPa, a well discernible characteristic vibrational mode (CC stretch) accompanied by several other spectral features such as δ CO
Identifiants
pubmed: 34627016
pii: S1386-1425(21)01015-5
doi: 10.1016/j.saa.2021.120438
pii:
doi:
Substances chimiques
Urocanic Acid
G8D26XJJ3B
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
120438Informations de copyright
Copyright © 2021 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.