Small molecule compounds with good anti-inflammatory activity reported in the literature from 01/2009 to 05/2021: a review.
Anti-inflammatory
biological activity
structure–activity relationship
synthesis
Journal
Journal of enzyme inhibition and medicinal chemistry
ISSN: 1475-6374
Titre abrégé: J Enzyme Inhib Med Chem
Pays: England
ID NLM: 101150203
Informations de publication
Date de publication:
Dec 2021
Dec 2021
Historique:
entrez:
11
10
2021
pubmed:
12
10
2021
medline:
27
1
2022
Statut:
ppublish
Résumé
Inflammation and disease are closely related. Inflammation can induce various diseases, and diseases can promote inflammatory response, and two possibly induces each other in a bidirectional loop. Inflammation is usually treated using synthetic anti-inflammatory drugs which are associated with several adverse effects hence are not safe for long-term use. Therefore, there is need for anti-inflammatory drugs which are not only effective but also safe. Several researchers have devoted to the research and development of effective anti-inflammatory drugs with little or no side effects. In this review, we studied some small molecules with reported anti-inflammatory activities and hence potential sources of anti-inflammatory agents. The information was retrieved from relevant studies published between January 2019 and May, 2021 for review. This review study was aimed to provide relevant information towards the design and development of effective and safe anti-inflammation agents.
Identifiants
pubmed: 34628990
doi: 10.1080/14756366.2021.1984903
pmc: PMC8516162
doi:
Substances chimiques
Anti-Inflammatory Agents, Non-Steroidal
0
Small Molecule Libraries
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
2139-2159Références
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