Updates in diagnosis and management of pancreatic cysts.

Carcinoembryonic antigen Endoscopic ultrasound-guided fine needle aspiration Intraductal papillary mucinous neoplasm Pancreatic cyst Serous cystadenoma Surveillance

Journal

World journal of gastroenterology
ISSN: 2219-2840
Titre abrégé: World J Gastroenterol
Pays: United States
ID NLM: 100883448

Informations de publication

Date de publication:
14 Sep 2021
Historique:
received: 28 02 2021
revised: 14 05 2021
accepted: 20 08 2021
entrez: 11 10 2021
pubmed: 12 10 2021
medline: 13 10 2021
Statut: ppublish

Résumé

Incidental pancreatic cysts are commonly encountered with some cysts having malignant potential. The most common pancreatic cystic neoplasms include serous cystadenoma, mucinous cystic neoplasm and intraductal papillary mucinous neoplasm. Risk stratifying pancreatic cysts is important in deciding whether patients may benefit from endoscopic ultrasound (EUS) or surgical resection. Surgery should be reserved for patients with malignant cysts or cysts at high risk for developing malignancy as suggested by various risk features including solid mass, nodule and dilated main pancreatic duct. EUS may supplement magnetic resonance imaging findings for cysts that remain indeterminate or have concerning features on imaging. Various cyst fluid markers including carcinoembryonic antigen, glucose, amylase, cytology, and DNA markers help distinguish mucinous from nonmucinous cysts. This review will guide the practicing gastroenterologist in how to evaluate incidental pancreatic cysts and when to consider referral for EUS or surgery. For presumed low risk cysts, surveillance strategies will be discussed. Managing pancreatic cysts requires an individualized approach that is directed by the various guidelines.

Identifiants

pubmed: 34629795
doi: 10.3748/wjg.v27.i34.5700
pmc: PMC8473602
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

5700-5714

Informations de copyright

©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflict-of-interest statement: No conflict of interest.

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Auteurs

Linda S Lee (LS)

Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women's Hospital, Boston, MA 02115, United States. llee@bwh.harvard.edu.

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