Liver Kidney Crosstalk: Hepatorenal Syndrome.

Acute kidney injury Crosstalk Hepatorenal syndrome Kidney Liver

Journal

World journal of hepatology
ISSN: 1948-5182
Titre abrégé: World J Hepatol
Pays: United States
ID NLM: 101532469

Informations de publication

Date de publication:
27 Sep 2021
Historique:
received: 28 02 2021
revised: 12 05 2021
accepted: 30 07 2021
entrez: 11 10 2021
pubmed: 12 10 2021
medline: 12 10 2021
Statut: ppublish

Résumé

The dying liver causes the suffocation of the kidneys, which is a simplified way of describing the pathophysiology of hepatorenal syndrome (HRS). HRS is characterized by reversible functional renal impairment due to reduced blood supply and glomerular filtration rate, secondary to increased vasodilators. Over the years, HRS has gained much attention and focus among hepatologists and nephrologists. HRS is a diagnosis of exclusion, and in some cases, it carries a poor prognosis. Different classifications have emerged to better understand, diagnose, and promptly treat this condition. This targeted review aims to provide substantial insight into the epidemiology, pathophysiology, diagnosis, and management of HRS, shed light on the various milestones of this condition, and add to our current understanding.

Identifiants

pubmed: 34630874
doi: 10.4254/wjh.v13.i9.1058
pmc: PMC8473490
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

1058-1068

Informations de copyright

©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflict-of-interest statement: The authors confirm the absence of personal and financial interests impacting the outcomes of this research study.

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Auteurs

Mahmoud Nassar (M)

Department of Medicine, Icahn School of Medicine at Mount Sinai / NYC Health + Hospitals / Queens, New York, NY 11432, United States.

Nso Nso (N)

Department of Medicine, Icahn School of Medicine at Mount Sinai / NYC Health + Hospitals / Queens, New York, NY 11432, United States.

Luis Medina (L)

Department of Medicine, Icahn School of Medicine at Mount Sinai / NYC Health + Hospitals / Queens, New York, NY 11432, United States.

Victoria Ghernautan (V)

Department of Medicine, Icahn School of Medicine at Mount Sinai / NYC Health + Hospitals / Queens, New York, NY 11432, United States.

Anastasia Novikov (A)

Department of Medicine, Icahn School of Medicine at Mount Sinai / NYC Health + Hospitals / Queens, New York, NY 11432, United States.

Alli El-Ijla (A)

Department of Medicine, Icahn School of Medicine at Mount Sinai / NYC Health + Hospitals / Queens, New York, NY 11432, United States.

Karim M Soliman (KM)

Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, United States.

Yungmin Kim (Y)

Department of Medicine, Icahn School of Medicine at Mount Sinai / NYC Health + Hospitals / Queens, New York, NY 11432, United States.

Mostafa Alfishawy (M)

Department of Infectious Diseases, Infectious Diseases Consultants and Academic Researchers of Egypt IDCARE, Cairo 11562, Egypt.

Vincent Rizzo (V)

Department of Medicine, Icahn School of Medicine at Mount Sinai / NYC Health + Hospitals / Queens, New York, NY 11432, United States.

Ahmed Daoud (A)

Department of Medicine, Kasr Alainy Medical School, Cairo University, Cairo 11211, Egypt. ahmed.daoud84@yahoo.com.

Classifications MeSH