Intraocular therapy in noninfectious uveitis.

Anti-tumor necrosis factor (TNF) α Anti-vascular endothelial growth factor (VEGF) Biologics Corticosteroids Immunosuppressive agents Intravitreal Local therapy Methotrexate Non-infectious uveitis

Journal

Journal of ophthalmic inflammation and infection
ISSN: 1869-5760
Titre abrégé: J Ophthalmic Inflamm Infect
Pays: Germany
ID NLM: 101553216

Informations de publication

Date de publication:
10 Oct 2021
Historique:
received: 01 01 2021
accepted: 19 09 2021
entrez: 11 10 2021
pubmed: 12 10 2021
medline: 12 10 2021
Statut: epublish

Résumé

Systemic corticosteroids and immunosuppressant agents are the mainstay of therapy for non-infectious uveitis (NIU). However, the risks associated with systemic administration and the need of delivering an effective and safe anti-inflammatory treatment targeted to the site of inflammation have prompt the use of local therapy in the management of NIU. This review will analyse the different local treatment options available, including corticosteroids, anti-vascular endothelial growth factor (VEGF), methotrexate and the recent biologics.

Identifiants

pubmed: 34632541
doi: 10.1186/s12348-021-00267-x
pii: 10.1186/s12348-021-00267-x
pmc: PMC8502718
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

37

Informations de copyright

© 2021. The Author(s).

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Auteurs

Rocco Luigi Modugno (RL)

Department of Neuroscience, Ophthalmology Unit, University of Padua, Padua, Italy.

Ilaria Testi (I)

Moorfields Eye Hospital, National Health Service Foundation Trust, 162 City Rd, Old Street, London, EC1V 2PD, UK.

Carlos Pavesio (C)

Moorfields Eye Hospital, National Health Service Foundation Trust, 162 City Rd, Old Street, London, EC1V 2PD, UK. c.pavesio@nhs.net.
Biomedical Research Centre, Institute of Ophthalmology, UCL, London, UK. c.pavesio@nhs.net.

Classifications MeSH