Neutralisation of SARS-CoV-2 by anatomical embalming solutions.
body donation
cadaver
fixation
preservation
Journal
Journal of anatomy
ISSN: 1469-7580
Titre abrégé: J Anat
Pays: England
ID NLM: 0137162
Informations de publication
Date de publication:
11 2021
11 2021
Historique:
revised:
18
09
2021
received:
30
07
2021
accepted:
06
09
2021
pubmed:
12
10
2021
medline:
23
11
2021
entrez:
11
10
2021
Statut:
ppublish
Résumé
Teaching and learning anatomy by using human cadaveric specimens has been a foundation of medical and biomedical teaching for hundreds of years. Therefore, the majority of institutions that teach topographical anatomy rely on body donation programmes to provide specimens for both undergraduate and postgraduate teaching of gross anatomy. The COVID-19 pandemic has posed an unprecedented challenge to anatomy teaching because of the suspension of donor acceptance at most institutions. This was largely due to concerns about the potential transmissibility of the SARS-CoV-2 virus and the absence of data about the ability of embalming solutions to neutralise the virus. Twenty embalming solutions commonly used in institutions in the United Kingdom and Ireland were tested for their ability to neutralise SARS-CoV-2, using an established cytotoxicity assay. All embalming solutions tested neutralised SARS-CoV-2, with the majority of solutions being effective at high-working dilutions. These results suggest that successful embalming with the tested solutions can neutralise the SARS-CoV-2 virus, thereby facilitating the safe resumption of body donation programmes and cadaveric anatomy teaching.
Identifiants
pubmed: 34633083
doi: 10.1111/joa.13549
pmc: PMC8546517
doi:
Substances chimiques
Fixatives
0
Formaldehyde
1HG84L3525
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1221-1225Subventions
Organisme : Royal College of Physicians and Surgeons of Glasgow
Organisme : National University of Ireland, Galway
Organisme : Imperial College London
Organisme : Anatomical Committee of the Dublin Medical Schools
Organisme : University of Cambridge
Organisme : University College Cork
Organisme : University of Aberdeen
Organisme : University of Dundee
Informations de copyright
© 2021 The Authors. Journal of Anatomy published by John Wiley & Sons Ltd on behalf of Anatomical Society.
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