Clinical Outcomes and Patient Satisfaction After Corneal Neurotization.
Journal
Cornea
ISSN: 1536-4798
Titre abrégé: Cornea
Pays: United States
ID NLM: 8216186
Informations de publication
Date de publication:
01 Nov 2021
01 Nov 2021
Historique:
received:
22
08
2020
accepted:
10
03
2021
entrez:
11
10
2021
pubmed:
12
10
2021
medline:
11
1
2022
Statut:
ppublish
Résumé
The aim of this study was to assess clinical outcomes of corneal neurotization (CN) and determine patient perception of postoperative results. This was a retrospective study involving 29 eyes in 28 patients who underwent CN. Chart review data included demographic and clinical history; ophthalmic examination including visual acuity, ocular surface quality, and corneal sensation; surgical technique; and postoperative course. Subjective self-reported patient outcomes of surgical success were also assessed. Only eyes with at least 6 months of follow-up were included in the statistical analysis. A total of 24 eyes and 23 patients were included in statistical analyses. The median postoperative follow-up time was 12.2 months (interquartile range 10.9-18.5 mo). Twenty-three eyes (92%) achieved improvement in ocular surface quality. Eleven of 13 (85%) demonstrated healing of persistent epithelial defects at their last follow-up. Patients gained a median of 2.3 cm in Cochet-Bonnet esthesiometry measurements of sensation. No significant difference was found between preoperative and postoperative visual acuity. All 17 patients who provided self-assessment of their surgical outcome indicated they would undergo CN again if given the choice. Most of the patients reported that the postoperative pain was tolerable, with a median pain score of 3.0 on a 10-point scale (interquartile range 0.0-4.0). Sixteen patients (94%) reported full or partial return of skin sensation along the donor nerve distribution. CN provides improvement in corneal health and sensibility, with high patient satisfaction and minimal postoperative pain and morbidity.
Identifiants
pubmed: 34633356
doi: 10.1097/ICO.0000000000002759
pii: 00003226-202111000-00003
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1377-1386Informations de copyright
Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.
Déclaration de conflit d'intérêts
I. M. Leyngold is a consultant for AxoGen Inc. The remaining authors have no conflicts of interest to disclose.
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