A multidisciplinary, collaborative, inter-agency and comprehensive approach for the control of Chagas Disease as a public health problem in Guatemala.


Journal

Acta tropica
ISSN: 1873-6254
Titre abrégé: Acta Trop
Pays: Netherlands
ID NLM: 0370374

Informations de publication

Date de publication:
Jan 2022
Historique:
received: 02 06 2021
revised: 10 09 2021
accepted: 20 09 2021
pubmed: 12 10 2021
medline: 30 11 2021
entrez: 11 10 2021
Statut: ppublish

Résumé

The Pan American Health Organization (PAHO) has defined Chagas Disease hotspots in Central America associated with the vector Triatoma spp. Triatoma dimidiata is a native vector adapted to multiple environments, including intra-domestic and peri-domestic habitats. A multi-institutional project named "Alliances for the elimination of Chagas in Central America" was created to help reduce the incidence of the disease in the region. Activities performed in the field as part of the project included aspects of vector surveillance and control, improvement of houses, diagnosis and treatment of individuals, health promotion, training of human resources and identification of access barriers to diagnosis and treatment. As a base line study, eleven villages, comprised of 1,572 households, were entomologically evaluated (83.4% overall participation); five were found to have very high infestation rates (>20%), three had high infestation rates (8-20%) and three had low-infestation rates (<8%), coinciding with the category of infestation-risk of the houses within each village. Serological tests were carried out in 812 people (>80% participation) in two of the 11 villages and none of the 128 children tested, less than 5 years of age, were positive for Trypanosoma cruzi infection. Community participation in all the activities was high (>70%). The collaboration between several subnational, national, and international institutions, each with specific roles, promoted community participation in the activities of vector control and patient care, thus, establishing a baseline to continue implementing and monitoring project progress.

Identifiants

pubmed: 34634265
pii: S0001-706X(21)00336-3
doi: 10.1016/j.actatropica.2021.106157
pii:
doi:

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

106157

Informations de copyright

Copyright © 2021. Published by Elsevier B.V.

Auteurs

María Carlota Monroy (MC)

University of San Carlos of Guatemala, Faculty of Chemical Sciences and Pharmacy, School of Biology, Laboratory of Applied Entomology and Parasitology (LENAP-USAC), Guatemala City, Guatemala. Electronic address: mcarlotamonroy@gmail.com.

Daniel Penados (D)

University of San Carlos of Guatemala, Faculty of Chemical Sciences and Pharmacy, School of Biology, Laboratory of Applied Entomology and Parasitology (LENAP-USAC), Guatemala City, Guatemala.

José Pineda (J)

University of San Carlos of Guatemala, Faculty of Chemical Sciences and Pharmacy, School of Biology, Laboratory of Applied Entomology and Parasitology (LENAP-USAC), Guatemala City, Guatemala.

Elisa Laparra Ruiz (EL)

University of San Carlos of Guatemala, Faculty of Chemical Sciences and Pharmacy, School of Biology, Laboratory of Applied Entomology and Parasitology (LENAP-USAC), Guatemala City, Guatemala.

Emmanuel O Agreda (EO)

University of San Carlos of Guatemala, Faculty of Chemical Sciences and Pharmacy, School of Biology, Laboratory of Applied Entomology and Parasitology (LENAP-USAC), Guatemala City, Guatemala.

Belter Alcantara (B)

University of San Carlos of Guatemala, Faculty of Chemical Sciences and Pharmacy, School of Biology, Laboratory of Applied Entomology and Parasitology (LENAP-USAC), Guatemala City, Guatemala.

Antonieta Rodas (A)

University of San Carlos of Guatemala, Faculty of Chemical Sciences and Pharmacy, School of Biology, Laboratory of Applied Entomology and Parasitology (LENAP-USAC), Guatemala City, Guatemala.

Karla Lange (K)

University of San Carlos of Guatemala, Faculty of Chemical Sciences and Pharmacy, School of Biological Chemistry, Department of Cytohistology, Guatemala City, Guatemala.

Diego Weinberg (D)

Fundación Mundo Sano (FMS), Buenos Aires City, Argentina.

Roberto Bazzani (R)

International Development Research Centre (IDRC), Canada.

Andrea Marchiol (A)

Drugs for Neglected Diseases initiative (DNDi), Rio de Janeiro, Brazil.

Rafael Herazo (R)

Drugs for Neglected Diseases initiative (DNDi), Rio de Janeiro, Brazil.

Roberto Salvatella Agrelo (RS)

Pan American Health Organization (PAHO/WHO), Uruguay.

Marcelo Abril (M)

Fundación Mundo Sano (FMS), Buenos Aires City, Argentina.

Roberto Chuit (R)

Fundación Mundo Sano (FMS), Buenos Aires City, Argentina.

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Classifications MeSH