Evolution of baseline characteristics and severe outcomes in COVID-19 inpatients during the first and second waves in Northeastern France.
COVID waves
COVID-19
Extrapulmonary complications
Outcome
SARS-CoV-2
Journal
Infectious diseases now
ISSN: 2666-9919
Titre abrégé: Infect Dis Now
Pays: France
ID NLM: 101775152
Informations de publication
Date de publication:
Feb 2022
Feb 2022
Historique:
received:
31
07
2021
revised:
03
09
2021
accepted:
05
10
2021
pubmed:
12
10
2021
medline:
2
2
2022
entrez:
11
10
2021
Statut:
ppublish
Résumé
Two COVID-19 epidemic waves occurred in France in 2020. This single-center retrospective study compared patients' characteristics and outcomes. We included all patients with confirmed COVID-19 admitted to Colmar Hospital in March (n=600) and October/November (n=205) 2020. Median ages, sex ratio, body mass index, and number of comorbidities were similar in wave 1 and 2 patients. Significant differences were found for temperature (38°C vs. 37.2), need for oxygen (38.6% vs. 26.8%), high-flow cannula (0% vs. 8.3%), and steroid use (6.3% vs. 54.1%). Intensive care unit (ICU) hospitalizations (25.5% vs. 15.1%, OR: 0.44, 95% CI [0.28; 0.68], P=0.002) and deaths (19.2% vs. 12.7%, OR: 0.61, 95% CI [0.37; 0.98], P=0.04) decreased during the second wave. Except for cardiovascular events (5.5% vs. 10.2%), no change was observed in extrapulmonary events. Deaths and ICU hospitalizations were significantly reduced during the second epidemic wave.
Identifiants
pubmed: 34634485
pii: S2666-9919(21)00514-5
doi: 10.1016/j.idnow.2021.10.002
pmc: PMC8500690
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
35-39Informations de copyright
Copyright © 2021 Elsevier Masson SAS. All rights reserved.
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