FullFix: a randomised controlled trial of a telephone delivered transdiagnostic intervention for comorbid substance and mental health problems in young people.
mental health
substance misuse
telemedicine
Journal
BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874
Informations de publication
Date de publication:
11 10 2021
11 10 2021
Historique:
entrez:
12
10
2021
pubmed:
13
10
2021
medline:
3
11
2021
Statut:
epublish
Résumé
Transdiagnostic cognitive-behavioural therapy (CBT) targets common psychological factors that underlie multiple disorders. While transdiagnostic interventions are a promising new approach, limited research has evaluated these treatments within the alcohol and other drug (AOD) sector for young people with comorbid mental health symptoms. This project will examine the feasibility and preliminary efficacy of FullFix-a new risk-targeted transdiagnostic CBT telehealth programme for comorbid AOD and depression/anxiety disorders in young people. Secondary aims are to identify moderators and mediators of treatment outcomes, to determine how and why treatment is effective and who is most likely to benefit. Participants will be 130 young people (aged 16-35) accessing AOD services in Queensland, Australia, with comorbid mental health symptoms. They will be randomised to receive either the FullFix intervention plus standard AOD care or standard AOD care alone. Primary outcomes on AOD use and mental health symptoms will be reassessed at 6 weeks, 3 months, 6 months and 12 months, along with secondary outcomes of emotion regulation, social connectedness, perceived self-efficacy, coping skills and quality of life. The trial commenced on October 2018 and expected completion date is September 2021. Ethical approval for this trial was provided by the University of Queensland (#2018001185). The results of the trial will be disseminated through publication in a peer-reviewed scientific journal, scientific presentations at conferences and distributed via a report and presentations to the partner organisation. ACTRN12618001563257.
Identifiants
pubmed: 34635511
pii: bmjopen-2020-045607
doi: 10.1136/bmjopen-2020-045607
pmc: PMC8506879
doi:
Types de publication
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e045607Informations de copyright
© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
Références
Arch Intern Med. 2006 May 22;166(10):1092-7
pubmed: 16717171
J Pers Disord. 2008 Aug;22(4):365-88
pubmed: 18684050
J Affect Disord. 2010 Feb;121(1-2):169-74
pubmed: 19604584
Drug Alcohol Rev. 2017 Jul;36(4):527-539
pubmed: 27786426
J Subst Abuse Treat. 2016 Feb;61:47-59
pubmed: 26531892
Subst Abuse Treat Prev Policy. 2015 Nov 11;10:45
pubmed: 26560076
Addict Behav. 2018 Sep;84:79-85
pubmed: 29631094
Curr Psychiatry Rep. 2019 Feb 7;21(2):10
pubmed: 30729322
Curr Addict Rep. 2015 Dec 1;2(4):354-363
pubmed: 26889402
Drug Alcohol Depend. 2016 Jun 01;163 Suppl 1:S3-S12
pubmed: 27306729
Addict Behav. 2012 Oct;37(10):1075-83
pubmed: 22698894
Drug Alcohol Rev. 2017 May;36(3):317-324
pubmed: 27324816
Eur J Public Health. 2006 Aug;16(4):420-8
pubmed: 16141303
Arch Gen Psychiatry. 2004 Aug;61(8):807-16
pubmed: 15289279
Aust N Z J Psychiatry. 2009 Jul;43(7):606-14
pubmed: 19530017
Psychother Psychosom. 2013;82(2):122-4
pubmed: 23295899
J Affect Disord. 2016 Jul 15;199:30-41
pubmed: 27060430
J Telemed Telecare. 2018 Feb;24(2):65-74
pubmed: 28038505
J Affect Disord. 2007 Nov;103(1-3):105-12
pubmed: 17291589
Addiction. 2021 Mar;116(3):474-484
pubmed: 32506558
Cogn Behav Ther. 2014;43(3):171-84
pubmed: 24646219
Aust N Z J Psychiatry. 2010 Aug;44(8):729-35
pubmed: 20636194
Behav Ther. 2016 Nov;47(6):854-868
pubmed: 27993337
Alcohol Clin Exp Res. 2005 Jul;29(7):1180-9
pubmed: 16046873
J Clin Med. 2020 Jul 28;9(8):
pubmed: 32731398
Arch Gen Psychiatry. 2005 Jun;62(6):617-27
pubmed: 15939839
Psychiatry Res. 2014 Oct 30;219(2):372-9
pubmed: 24953903
Asia Pac Psychiatry. 2016 Mar;8(1):3-22
pubmed: 26238088
Psychol Addict Behav. 2011 Sep;25(3):390-404
pubmed: 21823762
J Psychopathol Behav Assess. 2016 Jun;38(2):284-296
pubmed: 27239096
Addiction. 2001 Nov;96(11):1603-14
pubmed: 11784457
Br J Clin Psychol. 2018 Jun;57(2):186-202
pubmed: 29277906
Psychiatr Serv. 2001 May;52(5):597-9
pubmed: 11331791
Dev Psychopathol. 2016 Nov;28(4pt1):927-946
pubmed: 27739387
J Child Psychol Psychiatry. 2017 Sep;58(9):970-984
pubmed: 28548291
Behav Cogn Psychother. 2009 Jul;37(4):469-74
pubmed: 19545482
Subst Use Misuse. 2014 Apr;49(5):492-512
pubmed: 23461667
Cogn Behav Ther. 2011;40(2):111-25
pubmed: 21547778
Curr Opin Psychiatry. 2007 Jul;20(4):359-64
pubmed: 17551351
J Telemed Telecare. 2011;17(4):177-84
pubmed: 21357672
J Clin Child Adolesc Psychol. 2015;44(5):875-96
pubmed: 26016727
Gen Hosp Psychiatry. 2010 Jul-Aug;32(4):345-59
pubmed: 20633738
J Psychosom Res. 2010 Nov;69(5):511-20
pubmed: 20955871
J Clin Psychol. 2006 Mar;62(3):273-83
pubmed: 16299755
Am J Orthopsychiatry. 1996 Jan;66(1):17-31
pubmed: 8720638
J Abnorm Psychol. 2016 Oct;125(7):960-975
pubmed: 27732026
Am J Drug Alcohol Abuse. 2017 Jul;43(4):402-415
pubmed: 27494547
Clin Psychol Rev. 2017 Nov;57:141-163
pubmed: 28941927
Ann Intern Med. 2013 Feb 5;158(3):200-7
pubmed: 23295957
Neuropsychol Rehabil. 2008 Oct-Dec;18(5-6):671-91
pubmed: 18924001
Addict Behav. 2014 Sep;39(9):1372-6
pubmed: 24636739
Br J Gen Pract. 2008 Jan;58(546):32-6
pubmed: 18186994
Soc Psychiatry Psychiatr Epidemiol. 2015 Feb;50(2):171-82
pubmed: 25563838
Addiction. 2002 Sep;97(9):1183-94
pubmed: 12199834
BMC Emerg Med. 2014 Aug 08;14:19
pubmed: 25103779
Psychol Med. 2015 May;45(7):1551-63
pubmed: 25534496
Br J Addict. 1992 May;87(5):733-42
pubmed: 1591524
J Clin Psychol. 2003 Mar;59(3):351-62
pubmed: 12579550
J Gen Intern Med. 2001 Sep;16(9):606-13
pubmed: 11556941
J Med Internet Res. 2011 Dec 31;13(4):e126
pubmed: 22209829
Aust N Z J Psychiatry. 2007 Nov;41(11):896-902
pubmed: 17924242
Annu Rev Psychol. 1991;42:401-25
pubmed: 2018399
Drug Alcohol Depend. 2015 Feb 1;147:116-21
pubmed: 25533894
Eur Child Adolesc Psychiatry. 2006 Sep;15(6):319-28
pubmed: 16648966
BMC Psychiatry. 2016 Jul 19;16:250
pubmed: 27435013