Sacroiliac joint in sarcoidosis on computed tomography: a monocentric retrospective study (SISTER).


Journal

Rheumatology international
ISSN: 1437-160X
Titre abrégé: Rheumatol Int
Pays: Germany
ID NLM: 8206885

Informations de publication

Date de publication:
03 2022
Historique:
received: 21 06 2021
accepted: 01 10 2021
pubmed: 13 10 2021
medline: 8 3 2022
entrez: 12 10 2021
Statut: ppublish

Résumé

Sacroiliitis and spondyloarthritis (SpA) have been associated to sarcoidosis. Sarcoidosis bone involvement of the sacral or iliac bones has been reported to mimic SpA. We aimed to evaluate the prevalence of structural sacroiliitis and structural changes of the sacroiliac joints (SIJ) in patients with sarcoidosis by abdominal-pelvic computed tomography (AP-CT). In this monocentric retrospective study, three blinded readers evaluated AP-CT that had already been performed on patients with sarcoidosis and classified them as normal, degenerative, or inflammatory. A consensus was reached for the divergent cases. Erosion, ankylosis, and sclerosis, classically associated with sacroiliitis, were noted. SpA was defined according to the ASAS 2009 classification criteria. We identified 217 patients with proven sarcoidosis who underwent AP-CT. Only three patients had sacroiliitis by CT and four had SpA, representing 1.38% and 1.85% of the patients, respectively. Degenerative SIJs represented 28.1% of patients and were significantly associated with age, at least one pregnancy, rural lifestyle, ankylosis, diffuse idiopathic skeletal hyperostosis, sclerosis, and the presence of osteophytes. Four patients had axial bone sarcoidosis. Sacroiliitis, SpA, and degenerative changes of the SIJ have been highlighted by AP-CT in patients with sarcoidosis. Osteoarthritis of the SIJ in sarcoidosis was associated with age, pregnancy, and rural lifestyle. Further studies are needed to assess the link between SpA and sarcoidosis.

Identifiants

pubmed: 34636939
doi: 10.1007/s00296-021-05021-z
pii: 10.1007/s00296-021-05021-z
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

431-440

Informations de copyright

© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

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Auteurs

Simon Cadiou (S)

Department of Rheumatology, Rennes University Hospital, Hôpital Sud, University of Rennes 1, 16 Boulevard de Bulgarie, 35000, Rennes, France. simon.cadiou@chu-rennes.fr.

Guillaume Coiffier (G)

Department of Rheumatology, Dinan Hospital, 22000, Dinan, France.

Stéphane Jouneau (S)

Department of Respiratory Medicine, Rennes University Hospital, Rennes, France.
University of Rennes 1, Rennes, France.
INSERM-IRSET UMR1085, Rennes, France.

Patrick Jego (P)

Internal Medicine Department, Rennes University Hospital, University of Rennes 1, 35000, Rennes, France.

Aleth Perdriger (A)

Department of Rheumatology, Rennes University Hospital, Hôpital Sud, University of Rennes 1, 16 Boulevard de Bulgarie, 35000, Rennes, France.

Nicolas Belhomme (N)

Internal Medicine Department, Rennes University Hospital, 35000, Rennes, France.

Raphaël Guillin (R)

Department of Medical Imaging, Rennes University Hospital, 35000, Rennes, France.

Pascal Guggenbuhl (P)

Department of Rheumatology, Rennes University Hospital, Hôpital Sud, University of Rennes 1, 16 Boulevard de Bulgarie, 35000, Rennes, France.
INSERM, CHU Rennes, Institut NUMECAN (Nutrition Metabolisms and Cancer), UMR 1241, Univ Rennes, 35000, Rennes, France.

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