Hypoalbuminaemia and One-Year Mortality in Haemodialysis Patients with Heart Failure: A Cohort Analysis.
chronic haemodialysis
heart failure
hypoalbuminaemia
malnutrition
mortality
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
29 Sep 2021
29 Sep 2021
Historique:
received:
17
09
2021
revised:
25
09
2021
accepted:
27
09
2021
entrez:
13
10
2021
pubmed:
14
10
2021
medline:
14
10
2021
Statut:
epublish
Résumé
The prevalence of chronic kidney disease (CKD) and heart failure (HF) has been rising over the past decade, with a prevalence close to 40%. Cardiovascular disease and malnutrition are common comorbidities and known risk factors for mortality in haemodialysis (HD) patients. We aimed to evaluate the one-year mortality rate after dialysis induction, and the impact of serum albumin levels on survival outcomes, in patients with CKD and HF. This was a retrospective analysis of patients with CKD and HF who underwent chronic HD between January 2016 and December 2019 in a tertiary-care Portuguese hospital. Variables were submitted to univariate and multivariate analysis to determine factors predictive of one-mortality after HD start. In total, 204 patients were analysed (mean age 75.1 ± 10.3 years). Within the first year of HD start, 28.7% of patients died. These patients were significantly older [79.8 ± 7.2 versus 72.9 ± 10.9 years, In our cohort, older age, lower serum creatinine and lower serum albumin were independent risk factors for one-year mortality, highlighting the prognostic importance of malnutrition in patients starting chronic HD.
Identifiants
pubmed: 34640538
pii: jcm10194518
doi: 10.3390/jcm10194518
pmc: PMC8509659
pii:
doi:
Types de publication
Journal Article
Langues
eng
Références
Kidney Int. 2005 Oct;68(4):1766-76
pubmed: 16164653
BMC Nephrol. 2013 Nov 01;14:242
pubmed: 24499139
Blood Purif. 2004;22(1):175-80
pubmed: 14732826
Cardiorenal Med. 2020;10(6):452-461
pubmed: 33238287
BMC Nephrol. 2020 Sep 25;21(1):413
pubmed: 32977752
Indian J Clin Biochem. 2008 Jul;23(3):209-17
pubmed: 23105756
Hemodial Int. 2010 Apr;14(2):226-32
pubmed: 20345387
Semin Nephrol. 2018 Nov;38(6):600-617
pubmed: 30413254
Clin J Am Soc Nephrol. 2007 Jan;2(1):89-99
pubmed: 17699392
Clin J Am Soc Nephrol. 2011 Aug;6(8):1982-9
pubmed: 21784821
Eur J Intern Med. 2018 Jun;52:8-12
pubmed: 29680174
J Cachexia Sarcopenia Muscle. 2013 Mar;4(1):19-29
pubmed: 22777757
BMC Nephrol. 2020 Nov 23;21(1):502
pubmed: 33228547
Nutrients. 2018 Jan 11;10(1):
pubmed: 29324682
Kidney Int. 2019 Jun;95(6):1304-1317
pubmed: 31053387
Rev Cardiovasc Med. 2020 Mar 30;21(1):31-39
pubmed: 32259902
Nephrol Dial Transplant. 2018 Oct 1;33(suppl_3):iii28-iii34
pubmed: 30281132
Am J Nephrol. 2012;35(6):548-58
pubmed: 22677686
Kidney Int. 2002 Dec;62(6):2238-45
pubmed: 12427151
Am J Kidney Dis. 2003 Nov;42(5):864-81
pubmed: 14582032
Kidney Int. 1999 Feb;55(2):648-58
pubmed: 9987089