Hypoalbuminaemia and One-Year Mortality in Haemodialysis Patients with Heart Failure: A Cohort Analysis.

chronic haemodialysis heart failure hypoalbuminaemia malnutrition mortality

Journal

Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588

Informations de publication

Date de publication:
29 Sep 2021
Historique:
received: 17 09 2021
revised: 25 09 2021
accepted: 27 09 2021
entrez: 13 10 2021
pubmed: 14 10 2021
medline: 14 10 2021
Statut: epublish

Résumé

The prevalence of chronic kidney disease (CKD) and heart failure (HF) has been rising over the past decade, with a prevalence close to 40%. Cardiovascular disease and malnutrition are common comorbidities and known risk factors for mortality in haemodialysis (HD) patients. We aimed to evaluate the one-year mortality rate after dialysis induction, and the impact of serum albumin levels on survival outcomes, in patients with CKD and HF. This was a retrospective analysis of patients with CKD and HF who underwent chronic HD between January 2016 and December 2019 in a tertiary-care Portuguese hospital. Variables were submitted to univariate and multivariate analysis to determine factors predictive of one-mortality after HD start. In total, 204 patients were analysed (mean age 75.1 ± 10.3 years). Within the first year of HD start, 28.7% of patients died. These patients were significantly older [79.8 ± 7.2 versus 72.9 ± 10.9 years, In our cohort, older age, lower serum creatinine and lower serum albumin were independent risk factors for one-year mortality, highlighting the prognostic importance of malnutrition in patients starting chronic HD.

Identifiants

pubmed: 34640538
pii: jcm10194518
doi: 10.3390/jcm10194518
pmc: PMC8509659
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Ana Cardoso (A)

Centro Hospitalar Universitário Lisboa Norte, Department of Medicine, Division of Internal Medicine II, EPE, Av. Prof. Egas Moniz, 1649-035 Lisboa, Portugal.

Carolina Branco (C)

Centro Hospitalar Universitário Lisboa Norte, Department of Medicine, Division of Nephrology and Renal Transplantation, EPE, Av. Prof. Egas Moniz, 1649-035 Lisboa, Portugal.

Mariana Sant'Ana (M)

Clínica Universitária de Nefrologia, Faculdade de Medicina da Universidade de Lisboa, Universidade de Lisboa, Av. Prof. Egas Moniz, 1649-035 Lisboa, Portugal.

Cláudia Costa (C)

Centro Hospitalar Universitário Lisboa Norte, Department of Medicine, Division of Nephrology and Renal Transplantation, EPE, Av. Prof. Egas Moniz, 1649-035 Lisboa, Portugal.

Bernardo Silva (B)

Centro Hospitalar Universitário Lisboa Norte, Department of Medicine, Division of Nephrology and Renal Transplantation, EPE, Av. Prof. Egas Moniz, 1649-035 Lisboa, Portugal.

José Fonseca (J)

Centro Hospitalar Universitário Lisboa Norte, Department of Medicine, Division of Nephrology and Renal Transplantation, EPE, Av. Prof. Egas Moniz, 1649-035 Lisboa, Portugal.
Clínica Universitária de Nefrologia, Faculdade de Medicina da Universidade de Lisboa, Universidade de Lisboa, Av. Prof. Egas Moniz, 1649-035 Lisboa, Portugal.

Cristina Outerelo (C)

Centro Hospitalar Universitário Lisboa Norte, Department of Medicine, Division of Nephrology and Renal Transplantation, EPE, Av. Prof. Egas Moniz, 1649-035 Lisboa, Portugal.

Joana Gameiro (J)

Centro Hospitalar Universitário Lisboa Norte, Department of Medicine, Division of Nephrology and Renal Transplantation, EPE, Av. Prof. Egas Moniz, 1649-035 Lisboa, Portugal.
Clínica Universitária de Nefrologia, Faculdade de Medicina da Universidade de Lisboa, Universidade de Lisboa, Av. Prof. Egas Moniz, 1649-035 Lisboa, Portugal.

Classifications MeSH