Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases.

Humans Fluorodeoxyglucose F18 Glucose Microglia Neurodegenerative Diseases / diagnostic imaging Positron-Emission Tomography Animals Mice

Journal

Science translational medicine
ISSN: 1946-6242
Titre abrégé: Sci Transl Med
Pays: United States
ID NLM: 101505086

Informations de publication

Date de publication:
13 Oct 2021
Historique:
entrez: 13 10 2021
pubmed: 14 10 2021
medline: 3 11 2021
Statut: ppublish

Résumé

2-Deoxy-2-[

Identifiants

DOI: 10.1126/scitranslmed.abe5640 PMID: 34644146
pubmed: 34644146
doi: 10.1126/scitranslmed.abe5640
doi:

Substances chimiques

Fluorodeoxyglucose F18 0Z5B2CJX4D
Glucose IY9XDZ35W2

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

eabe5640

Commentaires et corrections

Type : CommentIn
Type : CommentIn

Auteurs

Xianyuan Xiang (X)

Biomedical Center (BMC), Division of Metabolic Biochemistry, Faculty of Medicine, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
CAS Key Laboratory of Brain Connectome and Manipulation, Brain Cognition and Brain Disease Institute, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences; Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, 518055 Shenzhen, China.
ORCID: 0000-0002-8125-9027

Karin Wind (K)

Department of Nuclear Medicine, University Hospital of Munich, LMU Munich, 81377 Munich, Germany.
German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.

Thomas Wiedemann (T)

Department of Nuclear Medicine, University Hospital of Munich, LMU Munich, 81377 Munich, Germany.

Tanja Blume (T)

Department of Nuclear Medicine, University Hospital of Munich, LMU Munich, 81377 Munich, Germany.
German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.

Yuan Shi (Y)

German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.

Nils Briel (N)

German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.
Center for Neuropathology and Prion Research, Ludwig-Maximilians-University München, 81377 Munich, Germany.
ORCID: 0000-0002-4349-3277

Leonie Beyer (L)

Department of Nuclear Medicine, University Hospital of Munich, LMU Munich, 81377 Munich, Germany.
ORCID: 0000-0002-7358-4495

Gloria Biechele (G)

Department of Nuclear Medicine, University Hospital of Munich, LMU Munich, 81377 Munich, Germany.

Florian Eckenweber (F)

Department of Nuclear Medicine, University Hospital of Munich, LMU Munich, 81377 Munich, Germany.

Artem Zatcepin (A)

Department of Nuclear Medicine, University Hospital of Munich, LMU Munich, 81377 Munich, Germany.
German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.
ORCID: 0000-0002-0224-088X

Sven Lammich (S)

Biomedical Center (BMC), Division of Metabolic Biochemistry, Faculty of Medicine, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.

Sara Ribicic (S)

German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.
ORCID: 0000-0002-1683-9842

Sabina Tahirovic (S)

German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.
ORCID: 0000-0003-4403-9559

Michael Willem (M)

Biomedical Center (BMC), Division of Metabolic Biochemistry, Faculty of Medicine, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
ORCID: 0000-0001-8829-3802

Maximilian Deussing (M)

Department of Nuclear Medicine, University Hospital of Munich, LMU Munich, 81377 Munich, Germany.

Carla Palleis (C)

German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.
Department of Neurology, University Hospital of Munich, LMU Munich, 81377 Munich, Germany.
ORCID: 0000-0002-4331-8145

Boris-Stephan Rauchmann (BS)

Department of Radiology, University Hospital of Munich, LMU Munich, 81377 Munich, Germany.
Department of Psychiatry and Psychotherapy, University Hospital of Munich, LMU Munich, 81377 Munich, Germany.
ORCID: 0000-0003-4547-6240

Franz-Josef Gildehaus (FJ)

Department of Nuclear Medicine, University Hospital of Munich, LMU Munich, 81377 Munich, Germany.

Simon Lindner (S)

Department of Nuclear Medicine, University Hospital of Munich, LMU Munich, 81377 Munich, Germany.

Charlotte Spitz (C)

Institute of Biochemistry and Molecular Biology, University of Augsburg, 86159 Augsburg, Germany.

Nicolai Franzmeier (N)

Institute for Stroke and Dementia Research (ISD), University Hospital of Munich, LMU Munich, 81377 Munich, Germany.
ORCID: 0000-0001-9736-2283

Karlheinz Baumann (K)

Roche, Pharma Research and Early Development, NORD DTA/Neuroscience Discovery, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Grenzacherstrasse 124, CH-4070 Basel, Switzerland.

Axel Rominger (A)

Department of Nuclear Medicine, University Hospital of Munich, LMU Munich, 81377 Munich, Germany.
Department of Nuclear Medicine, University of Bern, Inselspital, CH-3010 Bern, Switzerland.
ORCID: 0000-0002-1954-736X

Peter Bartenstein (P)

Department of Nuclear Medicine, University Hospital of Munich, LMU Munich, 81377 Munich, Germany.
Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany.

Sibylle Ziegler (S)

Department of Nuclear Medicine, University Hospital of Munich, LMU Munich, 81377 Munich, Germany.
Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany.

Alexander Drzezga (A)

Department of Nuclear Medicine, Faculty of Medicine, University Hospital Cologne, University of Cologne, 5091 Cologne, Germany.
German Center for Neurodegenerative Diseases (DZNE) Bonn-Cologne, 53127 Bonn, Germany.
Institute of Neuroscience and Medicine (INM-2), Molecular Organization of the Brain, Forschungszentrum Jülich, 52425 Jülich, Germany.

Gesine Respondek (G)

Department of Neurology, Hannover Medical School, 30625 Hannover, Germany.

Katharina Buerger (K)

German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.
Institute for Stroke and Dementia Research (ISD), University Hospital of Munich, LMU Munich, 81377 Munich, Germany.

Robert Perneczky (R)

German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.
Department of Psychiatry and Psychotherapy, University Hospital of Munich, LMU Munich, 81377 Munich, Germany.
Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany.
Ageing Epidemiology (AGE) Research Unit, School of Public Health, Imperial College, London SW7 2AZ, UK.
ORCID: 0000-0003-1981-7435

Johannes Levin (J)

German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.
Department of Neurology, University Hospital of Munich, LMU Munich, 81377 Munich, Germany.
Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany.
ORCID: 0000-0001-5092-4306

Günter U Höglinger (GU)

German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.
Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany.
Department of Neurology, Hannover Medical School, 30625 Hannover, Germany.
Department of Neurology, Technical University Munich, 81675 Munich, Germany.
ORCID: 0000-0001-7587-6187

Jochen Herms (J)

German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.
Center for Neuropathology and Prion Research, Ludwig-Maximilians-University München, 81377 Munich, Germany.
Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany.

Christian Haass (C)

Biomedical Center (BMC), Division of Metabolic Biochemistry, Faculty of Medicine, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.
Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany.
ORCID: 0000-0002-4869-1627

Matthias Brendel (M)

Department of Nuclear Medicine, University Hospital of Munich, LMU Munich, 81377 Munich, Germany.
German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.
Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany.
ORCID: 0000-0002-9247-2843

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Microglial activation states drive glucose...
questionsmedicales.fr › Glucides › Désoses › Désoxyglucose › Fluorodésoxyglucose F18 › Microglial activation states drive glucose...
questionsmedicales.fr › Glucides › Sucres › Oses › Hexose › Glucose › Microglial activation states drive glucose...
questionsmedicales.fr › Cellules › Névroglie › Microglie › Microglial activation states drive glucose...
questionsmedicales.fr › Maladies du système nerveux › Maladies neurodégénératives › Microglial activation states drive glucose...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic radioisotopique › Scintigraphie › Tomoscintigraphie › Tomographie par émission de positons › Microglial activation states drive glucose...
questionsmedicales.fr › Eucaryotes › Animaux › Microglial activation states drive glucose...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Microglial activation states drive glucose...