Effects of exercise on symptoms of anxiety in primary care patients: A randomized controlled trial.

Anxiety / therapy Anxiety Disorders / therapy Depression / therapy Exercise Humans Primary Health Care Quality of Life Treatment Outcome
Anxiety disorders Dose-response Exercise Intervention studies Primary health care Randomized Controlled Trial

Journal

Journal of affective disorders
ISSN: 1573-2517
Titre abrégé: J Affect Disord
Pays: Netherlands
ID NLM: 7906073

Informations de publication

Date de publication:
15 01 2022
Historique:
received: 30 07 2021
revised: 05 10 2021
accepted: 08 10 2021
pubmed: 14 10 2021
medline: 27 1 2022
entrez: 13 10 2021
Statut: ppublish

Résumé

There is a need for high-quality research regarding exercise interventions for persons with anxiety disorders. We investigate whether a 12-week exercise intervention, with different intensities, could reduce anxiety symptoms in patients with anxiety disorders. 286 patients were recruited from primary care in Sweden. Severity of symptoms was self-assessed using the Beck Anxiety Inventory (BAI) and the Montgomery Åsberg Depression Rating Scale (MADRS-S). Participants were randomly assigned to one of two group exercise programs with cardiorespiratory and resistance training and one control/standard treatment non-exercise group, with 1:1:1 allocation. Patients in both exercise groups showed larger improvements in both anxiety and depressive symptoms compared to the control group. No differences in effect sizes were found between the two groups. To study a clinically relevant improvement, BAI and MADRS-S were dichotomized with the mean change in the control group as reference. In adjusted models the odds ratio for improved symptoms of anxiety after low-intensity training was 3.62 (CI 1.34-9.76) and after moderate/high intensity 4.88 (CI 1.66-14.39), for depressive symptoms 4.96 (CI 1.81-13.6) and 4.36 (CI 1.57-12.08) respectively. There was a significant intensity trend for improvement in anxiety symptoms. The use of self-rating measures which bears the risk of an under- or overestimation of symptoms. A 12-week group exercise program proved effective for patients with anxiety syndromes in primary care. These findings strengthen the view of physical exercise as an effective treatment and could be more frequently made available in clinical practice for persons with anxiety issues.

Sections du résumé

BACKGROUND
There is a need for high-quality research regarding exercise interventions for persons with anxiety disorders. We investigate whether a 12-week exercise intervention, with different intensities, could reduce anxiety symptoms in patients with anxiety disorders.
METHODS
286 patients were recruited from primary care in Sweden. Severity of symptoms was self-assessed using the Beck Anxiety Inventory (BAI) and the Montgomery Åsberg Depression Rating Scale (MADRS-S). Participants were randomly assigned to one of two group exercise programs with cardiorespiratory and resistance training and one control/standard treatment non-exercise group, with 1:1:1 allocation.
RESULTS
Patients in both exercise groups showed larger improvements in both anxiety and depressive symptoms compared to the control group. No differences in effect sizes were found between the two groups. To study a clinically relevant improvement, BAI and MADRS-S were dichotomized with the mean change in the control group as reference. In adjusted models the odds ratio for improved symptoms of anxiety after low-intensity training was 3.62 (CI 1.34-9.76) and after moderate/high intensity 4.88 (CI 1.66-14.39), for depressive symptoms 4.96 (CI 1.81-13.6) and 4.36 (CI 1.57-12.08) respectively. There was a significant intensity trend for improvement in anxiety symptoms.
LIMITATIONS
The use of self-rating measures which bears the risk of an under- or overestimation of symptoms.
CONCLUSIONS
A 12-week group exercise program proved effective for patients with anxiety syndromes in primary care. These findings strengthen the view of physical exercise as an effective treatment and could be more frequently made available in clinical practice for persons with anxiety issues.

Identifiants

DOI: 10.1016/j.jad.2021.10.006 PMID: 34644619
pubmed: 34644619
pii: S0165-0327(21)01073-9
doi: 10.1016/j.jad.2021.10.006
pii:
doi:

Types de publication

Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

26-34

Commentaires et corrections

Type : ErratumIn

Informations de copyright

Copyright © 2021 The Author(s). Published by Elsevier B.V. All rights reserved.

Auteurs

Malin Henriksson (M)

School of Public Health and Community Medicine/Primary Health Care, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sweden; Region Västra Götaland, Närhälsan, Gothenburg, Sweden.

Alexander Wall (A)

Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sweden; Region Västra Götaland, Sahlgrenska University Hospital, Department of Acute Medicine and Geriatrics, Gothenburg, Sweden.

Jenny Nyberg (J)

Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Sweden; Region Västra Götaland, Sahlgrenska University Hospital, Neurology Clinic, Gothenburg, Sweden.

Martin Adiels (M)

Biostatistics, School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sweden.

Karin Lundin (K)

Region Västra Götaland, Regionhälsan, Gothenburg, Sweden.

Ylva Bergh (Y)

Region Västra Götaland, Närhälsan, Gothenburg, Sweden.

Robert Eggertsen (R)

School of Public Health and Community Medicine/Primary Health Care, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sweden; R&D Centre Gothenburg and Södra Bohuslän, Sweden.

Louise Danielsson (L)

Department of Health and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Sweden; Region Västra Götaland, Angered Hospital, Gothenburg, Sweden.

H Georg Kuhn (HG)

Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Sweden; Institute for Public Health, Charité - Universitätsmedizin Berlin, Berlin, Germany.

Maria Westerlund (M)

Region Västra Götaland, Regionhälsan, Gothenburg, Sweden.

N David Åberg (N)

Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sweden; Region Västra Götaland, Sahlgrenska University Hospital, Department of Acute Medicine and Geriatrics, Gothenburg, Sweden.

Margda Waern (M)

Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Sweden; Region Västra Götaland, Sahlgrenska University Hospital, Psychosis Clinic, Gothenburg, Sweden.

Maria Åberg (M)

School of Public Health and Community Medicine/Primary Health Care, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sweden; Region Västra Götaland, Regionhälsan, Gothenburg, Sweden. Electronic address: maria.aberg@gu.se.

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Classifications MeSH

questionsmedicales.fr › Comportement et mécanismes comportementaux › Émotions › Anxiété › Effects of exercise on symptoms of anxiety in...
questionsmedicales.fr › Troubles mentaux › Troubles anxieux › Effects of exercise on symptoms of anxiety in...
questionsmedicales.fr › Comportement et mécanismes comportementaux › Émotions › Dépression › Effects of exercise on symptoms of anxiety in...
questionsmedicales.fr › Activités humaines › Exercice physique › Effects of exercise on symptoms of anxiety in...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Effects of exercise on symptoms of anxiety in...
questionsmedicales.fr › Administration des services de santé › Gestion des soins aux patients › Services de santé polyvalents › Soins de santé primaires › Effects of exercise on symptoms of anxiety in...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Mesures épidémiologiques › Démographie › État de santé › Qualité de vie › Effects of exercise on symptoms of anxiety in...
questionsmedicales.fr › Qualité, accès, évaluation des soins de santé › Qualité des soins de santé › Mécanismes d'évaluation des soins de santé › Évaluation des résultats et des processus en soins de santé › Évaluation de résultat (soins) › Résultat thérapeutique › Effects of exercise on symptoms of anxiety in...