ALSUntangled #63: ketogenic diets.

Mice Animals Humans Diet, Ketogenic Amyotrophic Lateral Sclerosis
Ketone alsuntangled ketogenic diet mitochondria therapy transgenic animals

Journal

Amyotrophic lateral sclerosis & frontotemporal degeneration
ISSN: 2167-9223
Titre abrégé: Amyotroph Lateral Scler Frontotemporal Degener
Pays: England
ID NLM: 101587185

Informations de publication

Date de publication:
Feb 2023
Historique:
pubmed: 15 10 2021
medline: 26 1 2023
entrez: 14 10 2021
Statut: ppublish

Résumé

ALSUntangled reviews alternative and off label treatments with a goal of helping patients make more informed decisions about them. Here we review ketogenic diets. We shows that these have plausible mechanisms, including augmenting cellular energy balance and reducing excitotoxicity, neuroinflammation and oxidative stress. We review a mouse model study, anecdotal reports and trials in ALS and other diseases. We conclude that there is yet not enough data to recommend ketogenic diets for patients with ALS, especially in light of the many side effects these can have.

Identifiants

DOI: 10.1080/21678421.2021.1990346 PMID: 34645313
pubmed: 34645313
doi: 10.1080/21678421.2021.1990346
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

159-163

Auteurs

Richard Bedlack (R)

Neurology Department, Duke University, Durham, NC, United States.

Paul E Barkhaus (PE)

Neurology Department, Froedtert & the Medical College of Wisconsin, Kenosha, WI, United States.

Benjamin Barnes (B)

Neurology Department, Augusta University Medical College of Georgia, Augusta, GA, United States.

Morgan Beauchamp (M)

North Carolina State University, Raleigh, NC, United States.

Tulio Bertorini (T)

Neurology Department, The University of Tennessee Health Science Center VolShop Memphis, Memphis, TN, United States.

Mark B Bromberg (MB)

Neurology Department, University of Utah Health Hospitals and Clinics, Salt Lake City, UT, United States.

Gregory T Carter (GT)

St Lukes Rehabilitation Hospital, Physical Medicine and Rehabilitation, Chesterfield, MO, United States.

Vinay Chaudry (V)

Neurology Department, University of North Carolina School of Medicine Neuroscience Center, Chapel Hill, NC, United States.

Merit Cudkowicz (M)

Neurology Department, Mass General Brigham Inc., Boston, MA, United States.

Ce Jackson (C)

Neurology Department, The University of Texas Health Science Center at San Antonio - Greehey Academic and Research Campus, San Antonio, TX, United States.

Gleb Levitsky (G)

Real Health Clinic, Russian Federation.

Isaac Lund (I)

Green Hope High School, Cary, NC, United States.

Christopher McDermott (C)

The University of Sheffield Institute for Translational Neuroscience, Sheffield, United Kingdom.
ORCID: 0000-0002-1269-9053

Steven Novella (S)

Neurology Department, Yale University, New Haven, CT, United States.

Natasha Olby (N)

Neurology Department, North Carolina State University, Raleigh, NC, United States.

Lyle Ostrow (L)

Neurology Department, Johns Hopkins University, Baltimore, MD, United States.

Gary L Pattee (GL)

Neurology Department, University of Nebraska Medical Center College of Medicine, Omaha, NE, United States.

Terry Heiman-Patterson (T)

Neurology Department, Temple University, Philadelphia, PA, United States.

Dylan Ratner (D)

Longmeadow High School, Longmeadow, MA, United States.

Kristiana Salmon (K)

Neurology Department, McGill Centre for Research in Neuroscience, Montreal, Canada.

Susan Steves (S)

Nutrition Department, Duke University, Durham, NC, United States.

Mark Terrelonge (M)

Neurology Department, University of California San Francisco, San Francisco, CA, United States.

Paul Wicks (P)

Independent, Lichfield, GB.
ORCID: 0000-0002-2293-9284

Anne-Marie Wills (AM)

Neurology Department, Mass General Brigham Inc., Boston, MA, United States.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › ALSUntangled #63: ketogenic diets.
questionsmedicales.fr › Eucaryotes › Animaux › ALSUntangled #63: ketogenic diets.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › ALSUntangled #63: ketogenic diets.
questionsmedicales.fr › Phénomènes physiologiques › Alimentation et nutrition › Phénomènes physiologiques nutritionnels › Régime alimentaire › Régime pauvre en glucides › Régime cétogène › ALSUntangled #63: ketogenic diets.
questionsmedicales.fr › Maladies métaboliques et nutritionnelles › Maladies métaboliques › Troubles de l'homéostasie des protéines › Protéinopathies TDP-43 › Sclérose latérale amyotrophique › ALSUntangled #63: ketogenic diets.