HPV-driven anal neoplasia: review and recent developments.


Journal

Pathology
ISSN: 1465-3931
Titre abrégé: Pathology
Pays: England
ID NLM: 0175411

Informations de publication

Date de publication:
Mar 2022
Historique:
received: 01 07 2021
revised: 06 07 2021
accepted: 11 07 2021
pubmed: 15 10 2021
medline: 25 3 2022
entrez: 14 10 2021
Statut: ppublish

Résumé

A host of human papillomavirus (HPV)-associated squamous and glandular lesions may be identified in the anal canal in men and women. Given their relative rarity, familiarity with the morphological spectrum associated with HPV-driven anal neoplasia is important for proper identification and diagnosis. In this article, we review the classification and basic histopathological features of HPV-related squamous intraepithelial and invasive lesions as well as associated pitfalls. In addition, we provide an update on recently described HPV-driven, non-squamous tumours. As our experience with these lesions evolves, we expect the histological spectrum to further expand, particularly as it relates to non-squamous HPV-driven neoplasia.

Identifiants

pubmed: 34645567
pii: S0031-3025(21)00440-2
doi: 10.1016/j.pathol.2021.07.003
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

184-194

Informations de copyright

Copyright © 2021 Royal College of Pathologists of Australasia. Published by Elsevier B.V. All rights reserved.

Auteurs

Naziheh Assarzadegan (N)

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Eugene Brooks (E)

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Lysandra Voltaggio (L)

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: lvoltag1@jhmi.edu.

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Classifications MeSH