Unravelling the collateral damage of antibiotics on gut bacteria.


Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
11 2021
Historique:
received: 06 11 2019
accepted: 01 09 2021
pubmed: 15 10 2021
medline: 15 1 2022
entrez: 14 10 2021
Statut: ppublish

Résumé

Antibiotics are used to fight pathogens but also target commensal bacteria, disturbing the composition of gut microbiota and causing dysbiosis and disease

Identifiants

pubmed: 34646011
doi: 10.1038/s41586-021-03986-2
pii: 10.1038/s41586-021-03986-2
pmc: PMC7612847
mid: EMS145499
doi:

Substances chimiques

Anti-Bacterial Agents 0
Macrolides 0
Tetracyclines 0
Erythromycin 63937KV33D
Dicumarol 7QID3E7BG7

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

120-124

Subventions

Organisme : European Research Council
ID : 819454
Pays : International
Organisme : Medical Research Council
ID : MC_UU_00025/11
Pays : United Kingdom

Informations de copyright

© 2021. The Author(s), under exclusive licence to Springer Nature Limited.

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Auteurs

Lisa Maier (L)

Genome Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany. l.maier@uni-tuebingen.de.
Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Tübingen, Germany. l.maier@uni-tuebingen.de.
Cluster of Excellence 'Controlling Microbes to Fight Infections', University of Tübingen, Tübingen, Germany. l.maier@uni-tuebingen.de.

Camille V Goemans (CV)

Genome Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.

Jakob Wirbel (J)

Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.

Michael Kuhn (M)

Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.

Claudia Eberl (C)

Max-von-Pettenkofer Institute, LMU Munich, Munich, Germany.
German Center for Infection Research (DZIF), partner site LMU Munich, Munich, Germany.

Mihaela Pruteanu (M)

Genome Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
Department of Biology, Humboldt University Berlin, Berlin, Germany.

Patrick Müller (P)

Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Tübingen, Germany.
Cluster of Excellence 'Controlling Microbes to Fight Infections', University of Tübingen, Tübingen, Germany.

Sarela Garcia-Santamarina (S)

Genome Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.

Elisabetta Cacace (E)

Genome Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.

Boyao Zhang (B)

Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.

Cordula Gekeler (C)

Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Tübingen, Germany.
Cluster of Excellence 'Controlling Microbes to Fight Infections', University of Tübingen, Tübingen, Germany.

Tisya Banerjee (T)

Genome Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
Department of Chemistry, TU Munich, Munich, Germany.

Exene Erin Anderson (EE)

Genome Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
NYU School of Medicine, New York, NY, USA.

Alessio Milanese (A)

Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.

Ulrike Löber (U)

Experimental and Clinical Research Center, a cooperation of Charité - Universitätsmedizin Berlin and Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.
Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.

Sofia K Forslund (SK)

Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
Experimental and Clinical Research Center, a cooperation of Charité - Universitätsmedizin Berlin and Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.
Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.

Kiran Raosaheb Patil (KR)

Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
The Medical Research Council Toxicology Unit, University of Cambridge, Cambridge, UK.

Michael Zimmermann (M)

Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.

Bärbel Stecher (B)

Max-von-Pettenkofer Institute, LMU Munich, Munich, Germany.
German Center for Infection Research (DZIF), partner site LMU Munich, Munich, Germany.

Georg Zeller (G)

Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.

Peer Bork (P)

Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.
Yonsei Frontier Lab (YFL), Yonsei University, Seoul, South Korea.
Department of Bioinformatics, Biocenter, University of Würzburg, Würzburg, Germany.

Athanasios Typas (A)

Genome Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany. typas@embl.de.
Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany. typas@embl.de.

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