Structural basis of cytokine-mediated activation of ALK family receptors.
Anaplastic Lymphoma Kinase
/ chemistry
Binding Sites
Cytokines
/ chemistry
Enzyme Activation
Epidermal Growth Factor
/ chemistry
Glycine
HEK293 Cells
Humans
Models, Molecular
Multiprotein Complexes
/ chemistry
Mutation
Protein Binding
Protein Domains
Protein Multimerization
Receptor Protein-Tyrosine Kinases
/ chemistry
Substrate Specificity
Journal
Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462
Informations de publication
Date de publication:
12 2021
12 2021
Historique:
received:
24
03
2021
accepted:
25
08
2021
pubmed:
15
10
2021
medline:
2
2
2022
entrez:
14
10
2021
Statut:
ppublish
Résumé
Anaplastic lymphoma kinase (ALK)
Identifiants
pubmed: 34646012
doi: 10.1038/s41586-021-03959-5
pii: 10.1038/s41586-021-03959-5
pmc: PMC9343967
mid: NIHMS1819095
doi:
Substances chimiques
ALKAL1 protein, human
0
ALKAL2 protein, human
0
Cytokines
0
Multiprotein Complexes
0
Epidermal Growth Factor
62229-50-9
ALK protein, human
EC 2.7.10.1
Anaplastic Lymphoma Kinase
EC 2.7.10.1
LTK protein, human
EC 2.7.10.1
Receptor Protein-Tyrosine Kinases
EC 2.7.10.1
Glycine
TE7660XO1C
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
143-147Subventions
Organisme : NCI NIH HHS
ID : P30 CA008748
Pays : United States
Informations de copyright
© 2021. The Author(s), under exclusive licence to Springer Nature Limited.
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