Prevalence of autoimmune conditions in pregnant women in a tertiary maternity hospital: A cross-sectional survey and maternity database review.
Australia
Autoimmune disease
autoimmunity
pregnancy
prevalence
Journal
Obstetric medicine
ISSN: 1753-495X
Titre abrégé: Obstet Med
Pays: England
ID NLM: 101464191
Informations de publication
Date de publication:
Sep 2021
Sep 2021
Historique:
received:
31
07
2020
revised:
09
09
2020
accepted:
16
09
2020
entrez:
14
10
2021
pubmed:
15
10
2021
medline:
15
10
2021
Statut:
ppublish
Résumé
Autoimmune conditions are associated with adverse pregnancy and offspring outcomes; however, the prevalence in pregnant women is not well understood. Estimates based on administrative data alone may underestimate prevalence. A cross-sectional survey of women attending a tertiary referral hospital for antenatal care in December 2018-February 2019 and review of the hospital's maternity database of women giving birth from October 2017-June 2018 to estimate autoimmune disease prevalence. A total of 400 women completed surveys (78% response rate) and 41 (10.3%) reported an autoimmune disease, most commonly Hashimoto's thyroiditis (2.8%) and psoriasis (2.5%). From the maternity database, 112 of 2756 women giving birth (4.1%) had a recorded autoimmune disease, most commonly Hashimoto's thyroiditis (1.3%) followed by coeliac disease, Graves' disease, and immune thrombocytopenic purpura (all 0.4%). Autoimmune disease prevalence in pregnant women is higher when self-reported and may be more common than previously reported using administrative data.
Sections du résumé
BACKGROUND
BACKGROUND
Autoimmune conditions are associated with adverse pregnancy and offspring outcomes; however, the prevalence in pregnant women is not well understood. Estimates based on administrative data alone may underestimate prevalence.
METHODS
METHODS
A cross-sectional survey of women attending a tertiary referral hospital for antenatal care in December 2018-February 2019 and review of the hospital's maternity database of women giving birth from October 2017-June 2018 to estimate autoimmune disease prevalence.
RESULTS
RESULTS
A total of 400 women completed surveys (78% response rate) and 41 (10.3%) reported an autoimmune disease, most commonly Hashimoto's thyroiditis (2.8%) and psoriasis (2.5%). From the maternity database, 112 of 2756 women giving birth (4.1%) had a recorded autoimmune disease, most commonly Hashimoto's thyroiditis (1.3%) followed by coeliac disease, Graves' disease, and immune thrombocytopenic purpura (all 0.4%).
CONCLUSION
CONCLUSIONS
Autoimmune disease prevalence in pregnant women is higher when self-reported and may be more common than previously reported using administrative data.
Identifiants
pubmed: 34646344
doi: 10.1177/1753495X20964680
pii: 10.1177_1753495X20964680
pmc: PMC8504298
doi:
Types de publication
Journal Article
Langues
eng
Pagination
158-163Informations de copyright
© The Author(s) 2020.
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