A dynamic Markov model to assess the cost-effectiveness of the Kidney Team at Home intervention in The Netherlands.
Cost-effectiveness analysis
Home-based educational program
Markov model
Organ donation
Patient education
Journal
The European journal of health economics : HEPAC : health economics in prevention and care
ISSN: 1618-7601
Titre abrégé: Eur J Health Econ
Pays: Germany
ID NLM: 101134867
Informations de publication
Date de publication:
Jun 2022
Jun 2022
Historique:
received:
09
02
2021
accepted:
28
09
2021
pubmed:
15
10
2021
medline:
31
5
2022
entrez:
14
10
2021
Statut:
ppublish
Résumé
The Kidney Team at Home program is an educational intervention aimed at patients with chronic kidney disease to assist them in their choice for kidney replacement therapy. Previous studies have shown that the intervention results in an increase in knowledge and communication on kidney replacement therapy, and eventually in an increase in the number of living donor kidney transplantations. The study assesses the cost-effectiveness of the intervention compared to standard care. A dynamic probabilistic Markov model was used to estimate the monetary and health benefits of the intervention in The Netherlands over 10 years. Data on costs and health-related quality of life were derived from the literature. Transition probabilities, prevalence, and incidence rates were calculated using a large national database. An optimistic and a pessimistic implementation scenario were compared to a base case scenario with standard care. In both the optimistic and pessimistic scenario, the intervention is cost-effective and dominant compared to standard care: savings were €108,681,985 and €51,770,060 and the benefits were 1382 and 695 QALYs, respectively. The superior cost-effectiveness of the intervention is caused by the superior health effects and the reduction of costs associated with transplantation, and the relatively small incremental costs of the intervention. The favorable findings of this implementation project resulted in national uptake of the intervention in The Netherlands as of 2021. This is the first time a psychosocial intervention has been implemented as part of standard care in a kidney replacement therapy program worldwide.
Identifiants
pubmed: 34647158
doi: 10.1007/s10198-021-01383-0
pii: 10.1007/s10198-021-01383-0
pmc: PMC8513543
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
597-606Subventions
Organisme : Nierstichting (NL)
ID : A1D1P01
Informations de copyright
© 2021. The Author(s).
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