A contemporary review of therapeutic and regenerative management of intracerebral hemorrhage.
Journal
Annals of clinical and translational neurology
ISSN: 2328-9503
Titre abrégé: Ann Clin Transl Neurol
Pays: United States
ID NLM: 101623278
Informations de publication
Date de publication:
11 2021
11 2021
Historique:
revised:
25
06
2021
received:
30
06
2020
accepted:
03
08
2021
pubmed:
15
10
2021
medline:
1
3
2022
entrez:
14
10
2021
Statut:
ppublish
Résumé
Intracerebral hemorrhage (ICH) remains a common and debilitating form of stroke. This neurological emergency must be diagnosed and treated rapidly yet effectively. In this article, we review the medical, surgical, repair, and regenerative treatment options for managing ICH. Topics of focus include the management of blood pressure, intracranial pressure, coagulopathy, and intraventricular hemorrhage, as well as the role of surgery, regeneration, rehabilitation, and secondary prevention. Results of various phase II and III trials are incorporated. In summary, ICH patients should undergo rapid evaluation with neuroimaging, and early interventions should include systolic blood pressure control in the range of 140 mmHg, correction of coagulopathy if indicated, and assessment for surgical intervention. ICH patients should be managed in dedicated neurosurgical intensive care or stroke units where continuous monitoring of neurological status and evaluation for neurological deterioration is rapidly possible. Extravasation of hematoma may be helpful in patients with intraventricular extension of ICH. The goal of care is to reduce mortality and enable multimodal rehabilitative therapy.
Identifiants
pubmed: 34647437
doi: 10.1002/acn3.51443
pmc: PMC8607450
doi:
Substances chimiques
Hematologic Agents
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
2211-2221Informations de copyright
© 2021 The Authors. Annals of Clinical and Translational Neurology published by Wiley Periodicals LLC on behalf of American Neurological Association.
Références
Crit Pathw Cardiol. 2007 Mar;6(1):18-23
pubmed: 17667882
Neurology. 2008 Apr 15;70(16):1322-8
pubmed: 18256366
Neuron. 2010 Apr 29;66(2):198-204
pubmed: 20434997
Cochrane Database Syst Rev. 2018 May 23;5:CD007286
pubmed: 29791030
Stroke. 2012 Jan;43(1):67-71
pubmed: 21980211
Lancet. 2018 May 26;391(10135):2107-2115
pubmed: 29778325
Stroke. 2003 Jul;34(7):1710-6
pubmed: 12805495
Lancet Neurol. 2019 May;18(5):428-438
pubmed: 30898550
Lancet. 2013 Aug 3;382(9890):397-408
pubmed: 23726393
Neurology. 2014 Jun 17;82(24):2180-6
pubmed: 24838789
Stroke Res Treat. 2014;2014:234095
pubmed: 25126443
Disabil Rehabil. 2016;38(7):637-43
pubmed: 26079636
Stroke. 2012 Nov;43(11):2923-30
pubmed: 22989500
Neurol Med Chir (Tokyo). 2017 Nov 15;57(11):563-574
pubmed: 28819090
Neurocrit Care. 2013 Aug;19(1):19-24
pubmed: 23138543
J Stroke Cerebrovasc Dis. 2020 Mar;29(3):104583
pubmed: 31862153
Neurol Res Pract. 2019 May 10;1:12
pubmed: 33324878
N Engl J Med. 2013 Jun 20;368(25):2355-65
pubmed: 23713578
Stroke. 2017 Mar;48(3):596-603
pubmed: 28228576
Front Neurol. 2017 Mar 15;8:80
pubmed: 28360881
Lancet. 2017 Feb 11;389(10069):603-611
pubmed: 28081952
J Neurosurg. 2012 Oct;117(4):761-6
pubmed: 22880718
Lancet Neurol. 2016 Nov;15(12):1228-1237
pubmed: 27751554
Front Neurol. 2018 Dec 11;9:1091
pubmed: 30619050
Neurology. 2003 Nov 25;61(10):1351-6
pubmed: 14638954
Int J Stroke. 2019 Dec;14(9):987-995
pubmed: 30681042
JAMA. 1998 Dec 9;280(22):1930-5
pubmed: 9851479
J Stroke. 2017 Jan;19(1):28-39
pubmed: 28178413
Neurocrit Care. 2011 Apr;14(2):291-317
pubmed: 21080105
Neurocrit Care. 2016 Feb;24(1):47-60
pubmed: 26646118
Cerebrovasc Dis. 2005;19(2):96-101
pubmed: 15608433
Lancet Neurol. 2009 Apr;8(4):355-69
pubmed: 19233729
N Engl J Med. 2008 May 15;358(20):2127-37
pubmed: 18480205
Neurology. 2010 Oct 12;75(15):1333-42
pubmed: 20826714
Stroke. 2004 Jun;35(6):1364-7
pubmed: 15118169
Stroke. 2015 Jul;46(7):2032-60
pubmed: 26022637
Neuroepidemiology. 2020;54(2):171-179
pubmed: 32079017
J Neurol Sci. 2019 Mar 15;398:39-44
pubmed: 30682519
Acta Neurochir Suppl. 2008;105:43-6
pubmed: 19066080
Surg Neurol. 2005 Aug;64(2):160-4; discussion 164
pubmed: 16051011
J Neurol Neurosurg Psychiatry. 2007 Jul;78(7):729-31
pubmed: 17135457
Brain Pathol. 2018 Nov;28(6):844-859
pubmed: 30062722
Neurologia. 2013 May;28(4):236-49
pubmed: 21570742
Lancet. 2015 Nov 21;386(10008):2059-2068
pubmed: 26414968
J Clin Neurosci. 2002 Jan;9(1):4-8
pubmed: 11749009
Stroke Vasc Neurol. 2017 Feb 24;2(1):21-29
pubmed: 28959487
J Am Heart Assoc. 2015 May 06;4(5):
pubmed: 25950185
Int J Stroke. 2009 Feb;4(1):11-6
pubmed: 19236490
Int J Stroke. 2014 Aug;9(6):741-6
pubmed: 24025067
Neurology. 2006 Apr 25;66(8):1182-6
pubmed: 16636234
Clin Neurol Neurosurg. 2013 Jan;115(1):72-6
pubmed: 22657095
Neurology. 2010 Aug 24;75(8):693-8
pubmed: 20733144
J Neurol Neurosurg Psychiatry. 2007 Aug;78(8):836-40
pubmed: 17220294
Neurology. 2002 Jul 23;59(2):205-9
pubmed: 12136058
Stroke. 2018 Nov;49(11):2612-2620
pubmed: 30355183
Neurocrit Care. 2012 Feb;16(1):63-71
pubmed: 21847702
Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1590-5
pubmed: 19164589
Neurocrit Care. 2009;11(1):28-33
pubmed: 19238588
J Stroke Cerebrovasc Dis. 2016 Sep;25(9):2159-66
pubmed: 27289186
Crit Care. 2008;12(6):237
pubmed: 19108704
Neurocrit Care. 2013 Feb;18(1):59-63
pubmed: 21761271
Stroke. 2004 Jun;35(6):1415-20
pubmed: 15073385
Brain Inj. 2010;24(5):730-5
pubmed: 20334471
Lancet. 2005 Jan 29-Feb 4;365(9457):387-97
pubmed: 15680453
Sci Rep. 2016 Jul 07;6:29246
pubmed: 27385592
J Am Coll Cardiol. 1998 Aug;32(2):536-9
pubmed: 9708488
J Transl Med. 2011 Mar 22;9:29
pubmed: 21418664
Crit Care. 2015 Nov 17;19:409
pubmed: 26577436
Semin Neurol. 2016 Jun;36(3):306-12
pubmed: 27214706
Restor Neurol Neurosci. 2009;27(3):151-61
pubmed: 19531871
Neurology. 2020 Jan 21;94(3):e314-e322
pubmed: 31831597
N Engl J Med. 2009 Mar 26;360(13):1283-97
pubmed: 19318384
Crit Care Med. 2001 Mar;29(3):635-40
pubmed: 11373434
Lancet Neurol. 2005 Oct;4(10):662-72
pubmed: 16168935
Ann Neurol. 2012 Feb;71(2):199-205
pubmed: 22367992
Am J Cardiol. 2005 Dec 15;96(12):1731-3
pubmed: 16360366
Crit Care. 2020 Feb 7;24(1):45
pubmed: 32033578
Mediators Inflamm. 2015;2015:516740
pubmed: 25878400
Lancet Neurol. 2014 Apr;13(4):364-73
pubmed: 24530176
Stem Cells. 2019 Nov;37(11):1481-1491
pubmed: 31529663
Stroke. 2010 Dec;41(12):2860-6
pubmed: 21030703
Stem Cells Int. 2015;2015:318269
pubmed: 26240570
Stroke. 2019 Apr;50(4):939-946
pubmed: 30869568
J Stroke. 2017 Jan;19(1):3-10
pubmed: 28178408
Stroke. 2016 Nov;47(11):2749-2755
pubmed: 27758940
N Engl J Med. 2001 May 10;344(19):1450-60
pubmed: 11346811
Cerebrovasc Dis Extra. 2011 Jan-Dec;1(1):93-104
pubmed: 22566987
Stroke. 2010 Jun;41(6):1222-8
pubmed: 20431083
Stroke. 2011 Jun;42(6):1540-5
pubmed: 21512173
N Engl J Med. 2016 Sep 15;375(11):1033-43
pubmed: 27276234
QJM. 2013 Jan;106(1):11-25
pubmed: 23019591
J Stroke Cerebrovasc Dis. 2013 Jul;22(5):661-7
pubmed: 22633254
Lancet. 2019 Mar 9;393(10175):1021-1032
pubmed: 30739747
J Neurol Neurosurg Psychiatry. 2009 Aug;80(8):881-7
pubmed: 19332423