Eloquence-based reperfusion scoring and its ability to predict post-thrombectomy disability and functional status.


Journal

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences
ISSN: 2385-2011
Titre abrégé: Interv Neuroradiol
Pays: United States
ID NLM: 9602695

Informations de publication

Date de publication:
Oct 2022
Historique:
pubmed: 15 10 2021
medline: 28 9 2022
entrez: 14 10 2021
Statut: ppublish

Résumé

Angiographic reperfusion after endovascular thrombectomy in acute ischemic stroke is commonly graded using volume-based reperfusion scores such as the modified thrombolysis in cerebral infarct score. The location of non-reperfused regions is not included in modified thrombolysis in cerebral infarct score. We studied the predictive ability of an eloquence-based reperfusion score. Consecutive cases of endovascular thrombectomy for anterior circulation strokes performed between January 2018 and April 2020 were included. Digital subtraction angiograms were reviewed by two blinded neurointerventionalist operators. Incomplete reperfusion was further classified by lobar regions lacking reperfusion to create various cohorts. Outcomes were graded four to seven days post-procedure with the National Institute of Health Stroke Scale (NIHSS) and 90 days post-procedure with the modified Rankin Scale. One hundred patients were identified. Via multivariate analysis, we found that frontal lobe non-reperfusion (mean difference (MD) = -1.60, Eloquence-based reperfusion assessment is an important predictor for functional outcomes after thrombectomy.

Sections du résumé

BACKGROUND BACKGROUND
Angiographic reperfusion after endovascular thrombectomy in acute ischemic stroke is commonly graded using volume-based reperfusion scores such as the modified thrombolysis in cerebral infarct score. The location of non-reperfused regions is not included in modified thrombolysis in cerebral infarct score. We studied the predictive ability of an eloquence-based reperfusion score.
METHODS METHODS
Consecutive cases of endovascular thrombectomy for anterior circulation strokes performed between January 2018 and April 2020 were included. Digital subtraction angiograms were reviewed by two blinded neurointerventionalist operators. Incomplete reperfusion was further classified by lobar regions lacking reperfusion to create various cohorts. Outcomes were graded four to seven days post-procedure with the National Institute of Health Stroke Scale (NIHSS) and 90 days post-procedure with the modified Rankin Scale.
RESULTS RESULTS
One hundred patients were identified. Via multivariate analysis, we found that frontal lobe non-reperfusion (mean difference (MD) = -1.60,
CONCLUSIONS CONCLUSIONS
Eloquence-based reperfusion assessment is an important predictor for functional outcomes after thrombectomy.

Identifiants

pubmed: 34647489
doi: 10.1177/15910199211046424
pmc: PMC9511628
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

538-546

Subventions

Organisme : NINDS NIH HHS
ID : R21 NS109575
Pays : United States

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Auteurs

Elliot Pressman (E)

Department of Neurosurgery, 7831University of South Florida, USA.

Victoria Sands (V)

Department of Neurosurgery, 7831University of South Florida, USA.

Gabriel Flores (G)

Department of Neurosurgery, 7831University of South Florida, USA.

Liwei Chen (L)

Department of Internal Medicine, 7831University of South Florida, USA.

Rahul Mhaskar (R)

Department of Internal Medicine, 7831University of South Florida, USA.

Waldo R Guerrero (WR)

Department of Neurosurgery, 7831University of South Florida, USA.

Zeguang Ren (Z)

Department of Neurosurgery, 7831University of South Florida, USA.

Maxim Mokin (M)

Department of Neurosurgery, 7831University of South Florida, USA.

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Classifications MeSH