Turn on chemiluminescence-based probes for monitoring tyrosinase activity in conjunction with biological thiols.

Ascorbic Acid / chemistry Benzoquinones / chemistry Biosensing Techniques Cell Membrane Permeability Fluorescent Dyes / chemistry Glutathione / chemistry Humans Luminescent Measurements Monophenol Monooxygenase / analysis Oxidation-Reduction Structure-Activity Relationship Sulfhydryl Compounds / analysis

Journal

Chemical communications (Cambridge, England)
ISSN: 1364-548X
Titre abrégé: Chem Commun (Camb)
Pays: England
ID NLM: 9610838

Informations de publication

Date de publication:
28 Oct 2021
Historique:
pubmed: 15 10 2021
medline: 15 12 2021
entrez: 14 10 2021
Statut: epublish

Résumé

We report a chemiluminescent probe (CLPT1) that permits the paired detection of tyrosinase (Tyr) and biological thiols. Tyr only leads to a poor chemiluminescence response, a finding ascribed to the formation of a stable

Identifiants

DOI: 10.1039/d1cc05217a PMID: 34647549
pubmed: 34647549
doi: 10.1039/d1cc05217a
doi:

Substances chimiques

Benzoquinones 0
Fluorescent Dyes 0
Sulfhydryl Compounds 0
Monophenol Monooxygenase EC 1.14.18.1
Glutathione GAN16C9B8O
Ascorbic Acid PQ6CK8PD0R
2-benzoquinone SVD1LJ47R7

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

11386-11389

Subventions

Organisme : NCI NIH HHS
ID : R01 CA068682
Pays : United States

Auteurs

Omri Shelef (O)

School of Chemistry, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv, 69978, Israel. chdoron@tauex.tau.ac.il.

Adam C Sedgwick (AC)

Department of Chemistry, The University of Texas at Austin, 105 E 24th street A5300, Austin, TX, 78712-1224, USA. sessler@cm.utexas.edu.

Sabina Pozzi (S)

Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel. ronitsf@tauex.tau.ac.il.

Ori Green (O)

School of Chemistry, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv, 69978, Israel. chdoron@tauex.tau.ac.il.

Ronit Satchi-Fainaro (R)

Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel. ronitsf@tauex.tau.ac.il.

Doron Shabat (D)

School of Chemistry, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv, 69978, Israel. chdoron@tauex.tau.ac.il.
ORCID: 0000-0003-2502-639X

Jonathan L Sessler (JL)

Department of Chemistry, The University of Texas at Austin, 105 E 24th street A5300, Austin, TX, 78712-1224, USA. sessler@cm.utexas.edu.
ORCID: 0000-0002-9576-1325

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Glucides › Oses acides › Acide ascorbique › Turn on chemiluminescence-based probes for...
questionsmedicales.fr › Composés chimiques organiques › Quinones › Benzoquinones › Turn on chemiluminescence-based probes for...
questionsmedicales.fr › Techniques d'investigation › Techniques de sonde moléculaire › Techniques de biocapteur › Turn on chemiluminescence-based probes for...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Perméabilité des membranes cellulaires › Turn on chemiluminescence-based probes for...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Indicateurs et réactifs › Luminescents › Colorants fluorescents › Turn on chemiluminescence-based probes for...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Oligopeptides › Glutathion › Turn on chemiluminescence-based probes for...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Turn on chemiluminescence-based probes for...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Photométrie › Mesures de luminescence › Turn on chemiluminescence-based probes for...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Oxidoreductases › Oxygénases › Mixed function oxygenases › Catechol oxidase › Monophenol monooxygenase › Turn on chemiluminescence-based probes for...
questionsmedicales.fr › Métabolisme › Métabolisme énergétique › Oxydoréduction › Turn on chemiluminescence-based probes for...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Relation structure-activité › Turn on chemiluminescence-based probes for...
questionsmedicales.fr › Composés chimiques organiques › Composés du soufre › Thiols › Turn on chemiluminescence-based probes for...