GWAS Identifies Multiple Genetic Loci for Skin Color in Korean Women.
Journal
The Journal of investigative dermatology
ISSN: 1523-1747
Titre abrégé: J Invest Dermatol
Pays: United States
ID NLM: 0426720
Informations de publication
Date de publication:
04 2022
04 2022
Historique:
received:
21
04
2021
revised:
11
08
2021
accepted:
13
08
2021
pubmed:
15
10
2021
medline:
10
5
2022
entrez:
14
10
2021
Statut:
ppublish
Résumé
Human skin color is largely determined by genetic factors. Recent GWASs have reported several genetic variants associated with skin color, mostly in European and African populations. In this study, we performed GWAS in 17,019 Korean women to identify genetic variants associated with facial skin color, quantitatively measured as CIELAB color index. We identified variants in three, one, and six genomic loci associated with facial skin color index L∗, a∗, and b∗ values, respectively, and replicated the associations (combined analysis P-value < 5.0 × 10
Identifiants
pubmed: 34648798
pii: S0022-202X(21)02303-4
doi: 10.1016/j.jid.2021.08.440
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1077-1084Informations de copyright
Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.