Does a Monoblock Acetabular Component With a Ceramic Liner Cause More Pelvic Bone Loss Than a Conventional Modular Cementless Acetabular Component? A 2-Year Randomized Clinical Trial.


Journal

The Journal of arthroplasty
ISSN: 1532-8406
Titre abrégé: J Arthroplasty
Pays: United States
ID NLM: 8703515

Informations de publication

Date de publication:
01 2022
Historique:
received: 29 06 2021
revised: 19 08 2021
accepted: 30 08 2021
pubmed: 16 10 2021
medline: 28 1 2022
entrez: 15 10 2021
Statut: ppublish

Résumé

Ceramic-on-ceramic bearings permit the use of large femoral head size while maintaining a favorable effect on wear rates. However, because of increased device rigidity, periprosthetic bone quality could be negatively affected due to stress shielding. The purpose of this study is to assess pelvic periprosthetic bone remodeling around a monoblock ceramic-on-ceramic acetabular component compared to that around a conventional modular metal-on-polyethylene device. Participants were randomized to receive hip replacement using either a porous-coated, modular metal-on-polyethylene acetabular component (n = 46) or a hydroxyapatite and titanium-coated monoblock shell with an integrated ceramic-on-ceramic bearing (n = 40). Radiographic assessments were completed preoperatively and postoperatively, and measurements of bone mineral density (BMD) using dual-energy X-ray absorptiometry with region free analysis were performed postoperatively and over 2-years of follow-up. There was no significant difference in BMD between the 2 groups at baseline or over the following 2 years. At follow-up, complete shell-to-bone contact without a radiolucent line was observed in 26 (67%) of the modular devices and in 37 (93%) of monoblock (P < .001). The modular device was an independent predictor of radiolucent lines (odds ratio 19.1, P = .007). No cases underwent revision surgery for acetabular loosening. Both the porous-coated modular and hydroxyapatite-coated monoblock acetabular components showed successful clinical results at short-term follow-up with no difference in pixel-level BMD. Using a large head monoblock device does not appear to be associated with an adverse effect on the local bone environment when compared to a modular device. NCT: NCT01558752.

Sections du résumé

BACKGROUND
Ceramic-on-ceramic bearings permit the use of large femoral head size while maintaining a favorable effect on wear rates. However, because of increased device rigidity, periprosthetic bone quality could be negatively affected due to stress shielding. The purpose of this study is to assess pelvic periprosthetic bone remodeling around a monoblock ceramic-on-ceramic acetabular component compared to that around a conventional modular metal-on-polyethylene device.
METHODS
Participants were randomized to receive hip replacement using either a porous-coated, modular metal-on-polyethylene acetabular component (n = 46) or a hydroxyapatite and titanium-coated monoblock shell with an integrated ceramic-on-ceramic bearing (n = 40). Radiographic assessments were completed preoperatively and postoperatively, and measurements of bone mineral density (BMD) using dual-energy X-ray absorptiometry with region free analysis were performed postoperatively and over 2-years of follow-up.
RESULTS
There was no significant difference in BMD between the 2 groups at baseline or over the following 2 years. At follow-up, complete shell-to-bone contact without a radiolucent line was observed in 26 (67%) of the modular devices and in 37 (93%) of monoblock (P < .001). The modular device was an independent predictor of radiolucent lines (odds ratio 19.1, P = .007). No cases underwent revision surgery for acetabular loosening.
CONCLUSION
Both the porous-coated modular and hydroxyapatite-coated monoblock acetabular components showed successful clinical results at short-term follow-up with no difference in pixel-level BMD. Using a large head monoblock device does not appear to be associated with an adverse effect on the local bone environment when compared to a modular device. NCT: NCT01558752.

Identifiants

pubmed: 34649747
pii: S0883-5403(21)00711-7
doi: 10.1016/j.arth.2021.08.033
pii:
doi:

Banques de données

ClinicalTrials.gov
['NCT01558752']

Types de publication

Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

75-82

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Auteurs

Daniel Fischman (D)

Division of Orthopaedic Surgery, The Ottawa Hospital, Ottawa, Canada.

Mohit M Mahatma (MM)

Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK.

Pablo Slullitel (P)

Division of Orthopaedic Surgery, The Ottawa Hospital, Ottawa, Canada; Institute of Orthopaedics 'Carlos E. Ottolenghi', Italian Hospital of Buenos Aires, Buenos Aires, Argentina.

Mohsen Farzi (M)

Centre for Computational Imaging and Simulation Technologies in Bioscience, University of Leeds, Leeds, UK.

George Grammatopoulos (G)

Division of Orthopaedic Surgery, The Ottawa Hospital, Ottawa, Canada.

Stéphane Poitras (S)

School of Rehabilitation, Faculty of Health Sciences, University of Ottawa, Ottawa, Ontario, Canada.

J Mark Wilkinson (JM)

Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK.

Paul E Beaulé (PE)

Division of Orthopaedic Surgery, The Ottawa Hospital, Ottawa, Canada.

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