Tumor-Associated Microbiota in Proximal and Distal Colorectal Cancer and Their Relationships With Clinical Outcomes.

16S rRNA Fusobacteria clinical outcomes distal colorectal cancer microbiota proximal colon cancer

Journal

Frontiers in microbiology
ISSN: 1664-302X
Titre abrégé: Front Microbiol
Pays: Switzerland
ID NLM: 101548977

Informations de publication

Date de publication:
2021
Historique:
received: 20 06 2021
accepted: 17 08 2021
entrez: 15 10 2021
pubmed: 16 10 2021
medline: 16 10 2021
Statut: epublish

Résumé

The proximal and distal subsites of colorectal cancer (CRC) have distinct differences in their embryonic origin, epidemiology, and prognosis. Therefore, they are not considered as the same disease. However, the possible difference in microbial characterization of the two subsites of CRC is still unclear. In this study, we explored tumor microbiota diversity and composition difference in patients with proximal (

Identifiants

pubmed: 34650531
doi: 10.3389/fmicb.2021.727937
pmc: PMC8506159
doi:

Types de publication

Journal Article

Langues

eng

Pagination

727937

Informations de copyright

Copyright © 2021 Jin, Shang, Wu, Fan, Chen, Fan, Liu, Nie, Zhang, Cai, Ogino and Liu.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Min Jin (M)

Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Fumei Shang (F)

Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Department of Medical Oncology, Nanyang Central Hospital, Nanyang, China.

Jingjing Wu (J)

Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Qilin Fan (Q)

Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Chen Chen (C)

Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Jun Fan (J)

Department of Pathology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Li Liu (L)

Department of Epidemiology and Biostatistics, The Ministry of Education Key Lab of Environment and Health, School of Public Health, Huazhong University of Science and Technology, Wuhan, China.

Xiu Nie (X)

Department of Pathology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Tao Zhang (T)

Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Kailin Cai (K)

Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Shuji Ogino (S)

Program in Molecular Pathological Epidemiology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States.
Broad Institute of MIT and Harvard, Cambridge, MA, United States.
Cancer Immunology and Cancer Epidemiology Programs, Dana-Farber Harvard Cancer Center, Boston, MA, United States.

Hongli Liu (H)

Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Classifications MeSH