Biological Frailty Index in centenarians.
Biological frailty index
Biological reserves
Centenarians
Longevity
Journal
Aging clinical and experimental research
ISSN: 1720-8319
Titre abrégé: Aging Clin Exp Res
Pays: Germany
ID NLM: 101132995
Informations de publication
Date de publication:
Mar 2022
Mar 2022
Historique:
received:
22
07
2021
accepted:
28
09
2021
pubmed:
17
10
2021
medline:
8
3
2022
entrez:
16
10
2021
Statut:
ppublish
Résumé
This study measured the subclinical frailty of centenarians by looking at the accumulation of their biological abnormalities. For this aim, a biological Frailty Index (FI) was computed in centenarians living in Northern Italy. The median value of the biological FI was 0.33 (interquartile range, IQR 0.28-0.41). The biological FI did not significantly differ between women (0.34, IQR 0.31-0.39) and men (0.32, IQR 0.26-0.43). The biological FI seems to have a narrower distribution compared to clinical FI we previously computed in the same cohort. In conclusion, our study suggests that centenarians benefit from exceptional biological reserves that might be underestimated by clinical appearances.
Identifiants
pubmed: 34655428
doi: 10.1007/s40520-021-01993-x
pii: 10.1007/s40520-021-01993-x
pmc: PMC8894165
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
687-690Subventions
Organisme : ministero dell'istruzione, dell'università e della ricerca
ID : PRIN 2006
Organisme : ministero dell'istruzione, dell'università e della ricerca
ID : PRIN 2009
Informations de copyright
© 2021. The Author(s).
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