Autoimmune cerebellar hypermetabolism: Report of three cases and literature overview.

Encephalitis / diagnostic imaging Fluorodeoxyglucose F18 Hashimoto Disease Humans Magnetic Resonance Imaging Positron Emission Tomography Computed Tomography Positron-Emission Tomography
Autoimmune encephalitis Cerebellum Hypermetabolism Immune checkpoint inhibitor Ma2 PET-scanner Paraneoplastic Zic4

Journal

Revue neurologique
ISSN: 0035-3787
Titre abrégé: Rev Neurol (Paris)
Pays: France
ID NLM: 2984779R

Informations de publication

Date de publication:
Apr 2022
Historique:
received: 21 04 2021
revised: 19 07 2021
accepted: 23 07 2021
pubmed: 19 10 2021
medline: 17 5 2022
entrez: 18 10 2021
Statut: ppublish

Résumé

We report three cases of vermian cerebellar hypermetabolism in patients with autoimmune encephalitis. One of our patients was positive for anti-Ma2 antibodies and one for anti-Zic4 antibodies while the remaining patient did not present any known antibodies. The seronegative patient deteriorated after immune checkpoint inhibitor treatment for a pulmonary adenocarcinoma and improved with immunosuppressive drugs, which is in favour of an underlying autoimmune mechanism. They all presented with subacute neurological symptoms. Brain magnetic resonance imaging was normal except in one patient, where hyperintensities were present on FLAIR sequence around the third ventricle and the cerebral aqueduct.

Identifiants

DOI: 10.1016/j.neurol.2021.07.018 PMID: 34657731
pubmed: 34657731
pii: S0035-3787(21)00701-3
doi: 10.1016/j.neurol.2021.07.018
pii:
doi:

Substances chimiques

Fluorodeoxyglucose F18 0Z5B2CJX4D

Types de publication

Case Reports Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

337-346

Informations de copyright

Copyright © 2021 Elsevier Masson SAS. All rights reserved.

Auteurs

J-B Brunet de Courssou (JB)

Neurology department, Percy Military hospital, 92190 Clamart, France. Electronic address: jean-baptiste.brunet-de-courssou@aphp.fr.

M A Castilla-Lievre (MA)

Nuclear medicine department, Antoine-Béclère university Hospital, 92140 Clamart, France.

J Maillot (J)

Neurology department, Percy Military hospital, 92190 Clamart, France.

M-L Brechemier (ML)

Neurology department, Percy Military hospital, 92190 Clamart, France.

C Ohlmann (C)

Radiology department, Percy Military hospital, 92190 Clamart, France.

M Sallansonnet-Froment (M)

Neurology department, Percy Military hospital, 92190 Clamart, France.

C Tafani (C)

Neurology department, Percy Military hospital, 92190 Clamart, France.

D Psimaras (D)

Neurology department, neuro-oncology unit, Pitié-Salpêtrière university hospital, 75013 Paris, France.

D Ricard (D)

Neurology department, Percy Military hospital, 92190 Clamart, France; Centre Borelli, UMR 9010, université de Paris-Saclay, École normale supérieure Paris-Saclay, service de santé des armées, CNRS, université de Paris, INSERM, Paris, France.

F Bompaire (F)

Neurology department, Percy Military hospital, 92190 Clamart, France; Centre Borelli, UMR 9010, université de Paris-Saclay, École normale supérieure Paris-Saclay, service de santé des armées, CNRS, université de Paris, INSERM, Paris, France.

I Taifas (I)

Neurology department, Percy Military hospital, 92190 Clamart, France.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Maladies du système nerveux › Encéphalite › Autoimmune cerebellar hypermetabolism: Report...
questionsmedicales.fr › Glucides › Désoses › Désoxyglucose › Fluorodésoxyglucose F18 › Autoimmune cerebellar hypermetabolism: Report...
questionsmedicales.fr › Maladies endocriniennes › Maladies de la thyroïde › Thyroïdite › Maladie de Hashimoto › Autoimmune cerebellar hypermetabolism: Report...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Autoimmune cerebellar hypermetabolism: Report...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Imagerie diagnostique › Tomographie › Imagerie par résonance magnétique › Autoimmune cerebellar hypermetabolism: Report...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic radioisotopique › Scintigraphie › Tomoscintigraphie › Tomographie par émission de positons › Tomographie par émission de positons couplée à la tomodensitométrie › Autoimmune cerebellar hypermetabolism: Report...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic radioisotopique › Scintigraphie › Tomoscintigraphie › Tomographie par émission de positons › Autoimmune cerebellar hypermetabolism: Report...