Surgical Management of Locoregional Recurrence in Breast Cancer.
Re-irradiation
Recurrent breast cancer
Redo breast conservation surgery
Salvage mastectomy
Journal
Indian journal of surgical oncology
ISSN: 0975-7651
Titre abrégé: Indian J Surg Oncol
Pays: India
ID NLM: 101532448
Informations de publication
Date de publication:
Sep 2021
Sep 2021
Historique:
received:
28
10
2020
accepted:
29
04
2021
entrez:
18
10
2021
pubmed:
19
10
2021
medline:
19
10
2021
Statut:
ppublish
Résumé
Locoregional recurrences from breast cancer represent a heterogeneous group of disease that poses a therapeutic challenge and needs a multidisciplinary team management. The incidence of local recurrence after breast conservation surgery ranges from 10 to 22% and 5-15% after mastectomy at 10-year follow-up. Management of locoregional recurrence depends on tumor biology, stage at presentation, and prior local and systemic therapy. With improvements in diagnostic, pathological, and surgical techniques, radiation and systemic therapy approach, outcomes in these patients have improved. In this review, we discuss the risk factors, prognostic factors, surgical and reconstruction options, re-irradiation, and role of systemic therapy to define a reasonable treatment approach without compromising oncologic safety and achieve good cosmetic and survival outcomes.
Identifiants
pubmed: 34658592
doi: 10.1007/s13193-021-01342-4
pii: 1342
pmc: PMC8490535
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
616-623Informations de copyright
© Indian Association of Surgical Oncology 2021.
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