SARS-COV-2 Infection in Children and Red Blood Cell Distribution Width.
clinical outcomes
covid-19
covid-19 outcome predictor
erythrocyte indices
pediatrics emergency
prognostic role
red blood cell distribution width (rdw)
sars-cov-2 in children
severity of disease
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
Sep 2021
Sep 2021
Historique:
accepted:
08
09
2021
entrez:
18
10
2021
pubmed:
19
10
2021
medline:
19
10
2021
Statut:
epublish
Résumé
SARS-COV-2 infection due to Coronavirus is highly contagious and causes varying degrees of illness throughout the world. Recent literature has shown an association between red blood cell distribution width (RDW) and adverse outcomes among adult patients with COVID-19. Multiple hypotheses can explain the potential prognostic role of RDW in COVID-19 infection. The aim of this study is to describe RDW values in SARS-COV-2 infected children admitted to the Pediatric Emergency Department to shed light on the potential role of RDW as a prognostic factor in this specific group. Of 1086 tested children observed from March 2020 to April 2021, 36 positive SARS-COV-2 children (0-16 years) did not show clinically significant differences in RDW values according to illness categories, days of hospitalization, presence of multisystem inflammatory syndrome in children (MIS-C), or viral load (cycle threshold (CT) values). This study is the first to investigate this issue in a SARS-COV-2 infected pediatric population. Despite our negative results, given the high incidence of Delta variant in children, the low cost of the examination, its prognostic role described in adults, and its association to other pediatric illnesses, we believe that the role of RDW in SARS-COV-2 infected children should be deeper assessed and that larger collaborative studies on this issue are required.
Identifiants
pubmed: 34660044
doi: 10.7759/cureus.17837
pmc: PMC8501313
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e17837Informations de copyright
Copyright © 2021, Tchidjou Kuekou et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
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