Measuring forearm bone density instead of lumbar spine bone density improves the sensitivity of diagnosing osteoporosis in older adults with cardiovascular diseases: Data from SARCOS study.

Aortic calcification Distal forearm BMD Elderly Osteoporosis

Journal

Bone reports
ISSN: 2352-1872
Titre abrégé: Bone Rep
Pays: United States
ID NLM: 101646176

Informations de publication

Date de publication:
Dec 2021
Historique:
received: 07 08 2021
revised: 24 09 2021
accepted: 26 09 2021
entrez: 18 10 2021
pubmed: 19 10 2021
medline: 19 10 2021
Statut: epublish

Résumé

In older individuals with cardiovascular diseases, it has been challenging to diagnose osteoporosis due to aortic calcification and degenerative processes in the spine of older adults, especially in very old adults. To assess whether the distal forearm BMD with the proximal femur BMD has greater sensitivity for the diagnosis of osteoporosis than the lumbar spine BMD with the proximal femur BMD. We evaluated 515 older adults with cardiovascular disease from the SARCOS study and stratified them into under and over 80-year-old age groups and according to gender. Two diagnostic criteria were used to assess osteoporosis, SPF (lumbar spine and proximal femur BMD) and DFF (distal forearm and proximal femur BMD), which were compared with the multiple bone sites (MS) criteria (lumbar spine, distal radius, femoral neck, and total femur BMD). 43.9% were aged ≥80 years. Osteoporosis by SPF was diagnosed in 34% ( In the elderly population with cardiovascular disease evaluated in our study, the use of distal forearm BMD instead of lumbar spine BMD, associated with proximal femur BMD, showed higher sensitivity for the diagnosis of osteoporosis, regardless of gender, and especially among the very older adults.

Identifiants

pubmed: 34660851
doi: 10.1016/j.bonr.2021.101134
pii: S2352-1872(21)00391-0
pmc: PMC8502712
doi:

Types de publication

Journal Article

Langues

eng

Pagination

101134

Informations de copyright

© 2021 Published by Elsevier Inc.

Déclaration de conflit d'intérêts

oAlberto Frisoli Jr. declares that there is no conflict of interest.oAngela T Paes declares that there is no conflict of interest.oAmanda Diniz Kimura declares that there is no conflict of interest.oElaine Azevedo declares that there is no conflict of interestoValdir Ambrosio declares that there is no conflict of interest.oPrevious publicationoWe declare that the current version of this study has not been published in any medical journal.

Références

World Health Organ Tech Rep Ser. 1994;843:1-129
pubmed: 7941614
Osteoporos Int. 1997;7(5):407-13
pubmed: 9425497
Calcif Tissue Int. 2012 Dec;91(6):370-8
pubmed: 23052223
Osteoporos Int. 1997;7(6):564-9
pubmed: 9604053
Osteoporos Int. 2012 May;23(5):1533-9
pubmed: 21901478
Osteoporos Int. 2013 Jan;24(1):23-57
pubmed: 23079689
Circ Res. 2012 Apr 13;110(8):1097-108
pubmed: 22499900
Calcif Tissue Int. 2001 Jul;69(1):20-4
pubmed: 11685429
J Am Geriatr Soc. 1997 Feb;45(2):140-5
pubmed: 9033510
Osteoporos Int. 2012 Apr;23(4):1351-60
pubmed: 21720893
Osteoporos Int. 2000;11(7):592-9
pubmed: 11069193
Lancet. 1999 Sep 18;354(9183):971-5
pubmed: 10501357
Nat Rev Endocrinol. 2014 Jun;10(6):338-51
pubmed: 24751883
Osteoporos Int. 2013 Apr;24(4):1177-84
pubmed: 22872071
Acta Radiol. 1997 Mar;38(2):210-3
pubmed: 9093153
Eur J Clin Nutr. 2021 Mar;75(3):446-455
pubmed: 32948866
J Bone Miner Res. 1992 Jun;7(6):625-32
pubmed: 1414480
Arch Intern Med. 2007 Aug 13-27;167(15):1641-7
pubmed: 17698687
Bone. 2004 Jan;34(1):195-202
pubmed: 14751578
Osteoporos Int. 2014 Oct;25(10):2359-81
pubmed: 25182228
Endocr Pract. 2020 May;26(Suppl 1):1-46
pubmed: 32427503
Eur J Clin Invest. 1994 Dec;24(12):813-7
pubmed: 7705375
J Orthop Sci. 1998;3(1):3-9
pubmed: 9654549
Medicine (Baltimore). 2021 Jun 18;100(24):e26276
pubmed: 34128860
Bone Miner. 1992 Nov;19(2):185-94
pubmed: 1422314
Rheumatology (Oxford). 2012 Sep;51(9):1714-20
pubmed: 22661554
Osteoporos Int. 2007 Jan;18(1):35-43
pubmed: 16951907
Bone Rep. 2018 Dec 27;10:100190
pubmed: 30766896
J Clin Densitom. 2013 Oct-Dec;16(4):455-66
pubmed: 24183638
Osteoporos Int. 2006;17(4):527-34
pubmed: 16402164
Aging (Milano). 2000 Oct;12(5):360-5
pubmed: 11126522
Osteoporos Int. 2019 Jan;30(1):3-44
pubmed: 30324412
Osteoporos Int. 2004 Sep;15(9):724-8
pubmed: 14997287
J Clin Endocrinol Metab. 1991 Jun;72(6):1372-4
pubmed: 2026758
Osteoporos Int. 2002;13(2):105-12
pubmed: 11905520
J Gerontol A Biol Sci Med Sci. 2013 Oct;68(10):1243-51
pubmed: 23902935
JAMA. 2018 Jun 26;319(24):2532-2551
pubmed: 29946734
J Clin Endocrinol Metab. 2004 Sep;89(9):4246-53
pubmed: 15356016

Auteurs

Alberto Frisoli (A)

Geriatric Cardiology Clinic, Cardiology Division, Escola Paulista de Medicina, Universidade Federal de São Paulo, Brazil.
Elderly Vulnerability Disease Research Group - Cardiology Division, Escola Paulista de Medicina, Universidade Federal de São Paulo, Brazil.

Angela T Paes (AT)

Statistics Department, Universidade Federal de São Paulo, São Paulo, Brazil.

Amanda Diniz Kimura (AD)

Geriatric Cardiology Clinic, Cardiology Division, Escola Paulista de Medicina, Universidade Federal de São Paulo, Brazil.
Elderly Vulnerability Disease Research Group - Cardiology Division, Escola Paulista de Medicina, Universidade Federal de São Paulo, Brazil.

Elaine Azevedo (E)

Geriatric Cardiology Clinic, Cardiology Division, Escola Paulista de Medicina, Universidade Federal de São Paulo, Brazil.
Elderly Vulnerability Disease Research Group - Cardiology Division, Escola Paulista de Medicina, Universidade Federal de São Paulo, Brazil.

Valdir Ambrosio (V)

Geriatric Cardiology Clinic, Cardiology Division, Escola Paulista de Medicina, Universidade Federal de São Paulo, Brazil.

Classifications MeSH