Critically Ill Patient with Multidrug-Resistant Acinetobacter baumannii Respiratory Infection Successfully Treated with Intravenous and Nebulized Bacteriophage Therapy.
Acinetobacter
Acinetobacter baumannii
bacteriophage
bacteriophage therapy
mechanical ventilation
multidrug resistance
multidrug-resistant bacterial infection
Journal
Antimicrobial agents and chemotherapy
ISSN: 1098-6596
Titre abrégé: Antimicrob Agents Chemother
Pays: United States
ID NLM: 0315061
Informations de publication
Date de publication:
18 01 2022
18 01 2022
Historique:
pubmed:
19
10
2021
medline:
23
3
2022
entrez:
18
10
2021
Statut:
ppublish
Résumé
Hospitalized patients are at risk of developing serious multidrug resistant bacterial infections. This risk is heightened in patients who are on mechanical ventilation, are immunocompromised, and/or have chronic comorbidities. We report the case of a 52-year-old critically ill patient with a multidrug resistant Acinetobacter baumannii (MDR-A) respiratory infection who was successfully treated with antibiotics and intravenous and nebulized bacteriophage therapy.
Identifiants
pubmed: 34662188
doi: 10.1128/AAC.00824-21
pmc: PMC8765271
doi:
Substances chimiques
Anti-Bacterial Agents
0
Types de publication
Case Reports
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0082421Références
Nat Microbiol. 2021 Feb;6(2):157-161
pubmed: 33432151
Antibiotics (Basel). 2020 May 09;9(5):
pubmed: 32397354
Virol Sin. 2019 Aug;34(4):347-357
pubmed: 31093881
J Intensive Care. 2015 Mar 02;3:9
pubmed: 27408726
Adv Drug Deliv Rev. 2018 Aug;133:76-86
pubmed: 30096336
Pharmaceuticals (Basel). 2021 Jan 05;14(1):
pubmed: 33466546
Am J Infect Control. 2009 Dec;37(10):783-805
pubmed: 20004811
Bacteriophage. 2012 Jul 1;2(3):159-167
pubmed: 23275867
Antimicrob Agents Chemother. 2017 Sep 22;61(10):
pubmed: 28807909
Nat Rev Drug Discov. 2003 Jun;2(6):489-97
pubmed: 12776223
J Trauma Acute Care Surg. 2018 Jul;85(1S Suppl 2):S18-S26
pubmed: 29370056
Clin Infect Dis. 2019 Nov 13;69(11):2015-2018
pubmed: 30869755