Modifying the m
Journal
Molecular psychiatry
ISSN: 1476-5578
Titre abrégé: Mol Psychiatry
Pays: England
ID NLM: 9607835
Informations de publication
Date de publication:
12 2021
12 2021
Historique:
received:
27
07
2020
accepted:
25
08
2021
revised:
02
08
2021
pubmed:
20
10
2021
medline:
15
3
2022
entrez:
19
10
2021
Statut:
ppublish
Résumé
Synaptic plasticity processes, which underlie learning and memory formation, require RNA to be translated local to synapses. The synaptic tagging hypothesis has previously been proposed to explain how mRNAs are available at specific activated synapses. However how RNA is regulated, and which transcripts are silenced or processed as part of the tagging process is still unknown. Modification of RNA by N6-methyladenosine (m
Identifiants
pubmed: 34663904
doi: 10.1038/s41380-021-01282-z
pii: 10.1038/s41380-021-01282-z
pmc: PMC8872986
doi:
Substances chimiques
ALKBH5 protein, human
EC 1.14.11.-
AlkB Homolog 5, RNA Demethylase
EC 1.14.11.-
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
7141-7153Subventions
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/L013827/1
Pays : United Kingdom
Informations de copyright
© 2021. The Author(s).
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