ATS Core Curriculum 2021. Pediatric Pulmonary Medicine: Pulmonary Infections.

COVID-19 imaging immune compromise molecular diagnostics nontuberculous mycobacteria

Journal

ATS scholar
ISSN: 2690-7097
Titre abrégé: ATS Sch
Pays: United States
ID NLM: 101774447

Informations de publication

Date de publication:
Sep 2021
Historique:
received: 08 03 2021
accepted: 25 05 2021
entrez: 20 10 2021
pubmed: 21 10 2021
medline: 21 10 2021
Statut: epublish

Résumé

The following is a concise review of the Pediatric Pulmonary Medicine Core reviewing pediatric pulmonary infections, diagnostic assays, and imaging techniques presented at the 2021 American Thoracic Society Core Curriculum. Molecular methods have revolutionized microbiology. We highlight the need to collect appropriate samples for detection of specific pathogens or for panels and understand the limitations of the assays. Considerable progress has been made in imaging modalities for detecting pediatric pulmonary infections. Specifically, lung ultrasound and lung magnetic resonance imaging are promising radiation-free diagnostic tools, with results comparable with their radiation-exposing counterparts, for the evaluation and management of pulmonary infections. Clinicians caring for children with pulmonary disease should ensure that patients at risk for nontuberculous mycobacteria disease are identified and receive appropriate nontuberculous mycobacteria screening, monitoring, and treatment. Children with coronavirus disease (COVID-19) typically present with mild symptoms, but some may develop severe disease. Treatment is mainly supportive care, and most patients make a full recovery. Anticipatory guidance and appropriate counseling from pediatricians on social distancing and diagnostic testing remain vital to curbing the pandemic. The pediatric immunocompromised patient is at risk for invasive and opportunistic pulmonary infections. Prompt recognition of predisposing risk factors, combined with knowledge of clinical characteristics of microbial pathogens, can assist in the diagnosis and treatment of specific bacterial, viral, or fungal diseases.

Identifiants

pubmed: 34667993
doi: 10.34197/ats-scholar.2021-0034RE
pmc: PMC8518607
doi:

Types de publication

Journal Article

Langues

eng

Pagination

452-467

Subventions

Organisme : NHLBI NIH HHS
ID : T32 HL007633
Pays : United States

Informations de copyright

Copyright © 2021 by the American Thoracic Society.

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Auteurs

Jane E Gross (JE)

National Jewish Health, Denver, Colorado.

Michael Y McCown (MY)

Walter Reed National Military Medical Center, Bethesda, Maryland.

Caroline U A Okorie (CUA)

Stanford University, Stanford, California.

Lara C Bishay (LC)

Children's Hospital of Los Angeles, Los Angeles, California.

Fei J Dy (FJ)

University of Massachusetts Medical School, University of Massachusetts, Worcester, Massachusetts.

Carmen Leon Astudillo (CL)

University of Florida, Gainesville, Florida.

Marianne S Muhlebach (MS)

University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

Sara Abu-Nassar (S)

University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

Diana Y Chen (DY)

Stanford University, Stanford, California.

Nazia Hossain (N)

Stanford University, Stanford, California.

Ruobing Wang (R)

Boston Children's Hospital, Boston, Massachusetts.

Timothy Klouda (T)

Boston Children's Hospital, Boston, Massachusetts.

Stacey L Martiniano (SL)

Children's Hospital Colorado, University of Colorado, Aurora, Colorado.

Patricia Lenhart-Pendergrass (P)

Children's Hospital Colorado, University of Colorado, Aurora, Colorado.

Stephen Kirkby (S)

Nationwide Children's Hospital, Columbus, Ohio.

Robin Ortenberg (R)

Nationwide Children's Hospital, Columbus, Ohio.

Jakob I McSparron (JI)

University of Michigan, Ann Arbor, Michigan.

Tisha Wang (T)

University of California, Los Angeles, California.

Margaret M Hayes (MM)

Beth Israel Deaconess Medical Center, Boston, Massachusetts; and.

Başak Çoruh (B)

University of Washington, Seattle, Washington.

Classifications MeSH