Transcatheter Arterial Embolization Using Imipenem/Cilastatin Sodium for Chronic Low Back Pain Resistant to Conservative Treatment: A Pilot Study with 2-Year Follow-Up.
Brief pain inventory score
Chronic low back pain
Oswestry disability index
Transcatheter arterial embolization
Journal
Cardiovascular and interventional radiology
ISSN: 1432-086X
Titre abrégé: Cardiovasc Intervent Radiol
Pays: United States
ID NLM: 8003538
Informations de publication
Date de publication:
Dec 2021
Dec 2021
Historique:
received:
07
04
2021
accepted:
27
08
2021
pubmed:
21
10
2021
medline:
1
12
2021
entrez:
20
10
2021
Statut:
ppublish
Résumé
To evaluate the safety and 2-year follow-up clinical outcomes of transcatheter arterial embolization (TAE) using imipenem/cilastatin sodium for chronic low back pain resistant to conservative treatment. A retrospective review identified 14 patients who underwent TAE for chronic low back pain between October 2017 and August 2018. Patients with low back pain related to the facet or sacroiliac joint, lasting ≥ 6 months, refractory to ≥ 3 months of conservative treatment were eligible for TAE. Each patient received embolization of feeding arteries of painful regions. The changes in brief pain inventory (BPI) scores, adverse events, and the Oswestry Disability Index (ODI) were evaluated at baseline and 1, 3, and 24 months after TAE. Clinical success was defined as BPI maximum pain intensity decrease of ≥ 2 and ODI decrease of ≥ 10 points from baseline. Follow-up data were available in 13 and 11 patients, at 3 and 24 months after embolization, respectively. Intention-to-treat clinical success was obtained in 11/14 (79%) of patients at 3 months and 8/14 (57%) of patients at 24 months after TAE. Mean BPI maximum pain intensity and ODI scores decreased significantly from baseline to 1, 3, and 24 months after treatment (7.6 vs.. 4.3, 3.4, and 4.1; 40.8 vs 21.5, 20.0, and 23.8, respectively; all P < 0.01). No major adverse events were associated with the procedures. TAE is one possible treatment option for patients with chronic low back pain refractory to conservative treatment.
Identifiants
pubmed: 34668999
doi: 10.1007/s00270-021-02976-1
pii: 10.1007/s00270-021-02976-1
doi:
Substances chimiques
Cilastatin, Imipenem Drug Combination
92309-29-0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1964-1970Informations de copyright
© 2021. Springer Science+Business Media, LLC, part of Springer Nature and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE).
Références
Maher C, Underwood M, Buchbinder R. Non-specific low back pain. Lancet. 2017;389:736–47.
doi: 10.1016/S0140-6736(16)30970-9
Dagenais S, Tricco AC, Haldeman S. Synthesis of recommendations for the assessment and management of low back pain from recent clinical practice guidelines. Spine J. 2010;10:514–29.
doi: 10.1016/j.spinee.2010.03.032
Koes BW, van Tulder MW, Thomas S. Diagnosis and treatment of low back pain. BMJ. 2006;332:1430–4.
doi: 10.1136/bmj.332.7555.1430
Manchikanti L, Pampati V, Fellows B, Bakhit CE. Prevalence of lumbar facet joint pain in chronic low back pain. Pain Phys. 1999;2:59–64.
doi: 10.36076/ppj.1999/2/59
Bogduk N. The anatomical basis for spinal pain syndromes. J Manipulative Physiol Ther. 1995;18:603–5.
pubmed: 8775022
Staal JB, de Bie R, de Vet HC, Hildebrandt J, Nelemans P. Injection therapy for subacute and chronic low-back pain. Cochrane Database Syst Rev. 2008;2008:CD001824.
pmcid: 7096223
Juch JNS, Maas ET, Ostelo RWJG, et al. Effect of radiofrequency denervation on pain intensity among patients with chronic low back pain the mint randomized. Clin Trials. 2017;318:68–81.
Suzuki H, Kanchiku T, Imajo Y, et al. Diagnosis and characters of non-specific low back pain in Japan: the Yamaguchi low back pain study. PLoS ONE. 2016;11:1–13.
Iwamoto W, Okuno Y, Matsumura N, Kaneko T, Ikegami H. Transcatheter arterial embolization of abnormal vessels as a treatment for lateral epicondylitis refractory to conservative treatment: a pilot study with a 2-year follow-up. J Shoulder Elb Surg. 2017;26:1335–41.
doi: 10.1016/j.jse.2017.03.026
Okuno Y, Korchi AM, Shinjo T, Kato S. Transcatheter arterial embolization as a treatment for medial knee pain in patients with mild to moderate osteoarthritis. Cardiovasc Interv Radiol. 2015;38:336–43.
doi: 10.1007/s00270-014-0944-8
Okuno Y, Oguro S, Iwamoto W, Miyamoto T, Ikegami H, Matsumura N. Short-term results of transcatheter arterial embolization for abnormal neovessels in patients with adhesive capsulitis: a pilot study. J shoulder Elb Surg. 2014;23:e199-206.
doi: 10.1016/j.jse.2013.12.014
Bagla S, Piechowiak R, Hartman T, Orlando J, Del Gaizo D, Isaacson A. Genicular artery embolization for the treatment of knee pain secondary to osteoarthritis. J Vasc Interv Radiol. 2020;31:1096–102.
doi: 10.1016/j.jvir.2019.09.018
Hwang JH, Park SW, Kim KH, Lee SJ, Oh KS, Chung SW, et al. Early results of transcatheter arterial embolization for relief of chronic shoulder or elbow pain associated with tendinopathy refractory to conservative treatment. J Vasc Interv Radiol. 2018;29:510–7. https://doi.org/10.1016/j.jvir.2017.11.013 .
doi: 10.1016/j.jvir.2017.11.013
pubmed: 29477621
Little MW, Gibson M, Briggs J, et al. Genicular artery embolization in patients with osteoarthritis of the knee (GENESIS) using permanent microspheres: interim analysis. Cardiovasc Interv Radiol. 2021;44:931–40.
doi: 10.1007/s00270-020-02764-3
Lee SH, Hwang JH, Kim DH, So YH, Park J, Cho SB, et al. Clinical outcomes of transcatheter arterial embolisation for chronic knee pain: mild-to-moderate versus severe knee osteoarthritis. Cardiovasc Intervent Radiol. 2019;42:1530–6.
doi: 10.1007/s00270-019-02289-4
Yoshioka K, Niinuma H, Ehara S, Nakajima T, Nakamura M, Kawazoe K. MR angiography and CT angiography of the artery of Adamkiewicz: state of the art. Radiogr Rev Publ Radiol Soc. 2006;26(Suppl 1):S63-73.
Yamada K, Jahangiri Y, Li J, et al. Embolic characteristics of imipenem-cilastatin particles in vitro and in vivo: implications for transarterial embolization in joint arthropathies. J Vasc Interv Radiol. 2021;32:1031-1039.e2.
doi: 10.1016/j.jvir.2021.02.006
Tan G, Jensen MP, Thornby JI, Shanti BFJ. Validation of the brief pain inventory for chronic nonmalignant pain. J Pain. 2004;5:133–7.
doi: 10.1016/j.jpain.2003.12.005
Hägg O, Fritzell P, Nordwall A. The clinical importance of changes in outcome scores after treatment for chronic low back pain. Eur Spine J. 2003;12:12–20.
doi: 10.1007/s00586-002-0464-0
Deyo RA, Weinstein JN. Low back pain. N Engl J Med. 2001;344:363–70.
doi: 10.1056/NEJM200102013440508
Alfredson H, Ohberg L, Forsgren S. Is vasculo-neural ingrowth the cause of pain in chronic Achilles tendinosis? An investigation using ultrasonography and colour doppler, immunohistochemistry, and diagnostic injections. Knee Surg Sports Traumatol Arthrosc. 2003;11:334–8.
doi: 10.1007/s00167-003-0391-6
Walsh DA, Bonnet CS, Turner EL, Wilson D, Situ M, McWilliams DF. Angiogenesis in the synovium and at the osteochondral junction in osteoarthritis. Osteoarthr Cartil. 2007;15:743–51.
doi: 10.1016/j.joca.2007.01.020
Xu Y, Bonar F, Murrell GAC. Enhanced expression of neuronal proteins in idiopathic frozen shoulder. J Shoulder Elb Surg. 2012;21:1391–7.
doi: 10.1016/j.jse.2011.08.046
Taguchi H, Tanaka T, Nishiofuku H, Fukuoka Y, Minamiguchi K, Taiji R, et al. A rat model of frozen shoulder demonstrating the effect of transcatheter arterial embolization on angiography, histopathology, and physical activity. J Vasc Interv Radiol. 2021;32:376–83.
doi: 10.1016/j.jvir.2020.10.017
Grönblad M, Korkala O, Konttinen YT, Nederström A, Hukkanen M, Tolvanen E, et al. Silver impregnation and immunohistochemical study of nerves in lumbar facet joint plical tissue. Spine. 1991;16:34–8.
doi: 10.1097/00007632-199101000-00006
Pinheiro MB, Ferreira ML, Refshauge K, et al. Symptoms of depression and risk of new episodes of low back pain: a systematic review and meta-analysis. Arthritis Care Res. 2015;67:1591–603.
doi: 10.1002/acr.22619