Interrelationships among whole-body skeletal muscle mass, masseter muscle mass, oral function, and dentition status in older Japanese adults.
Cross-sectional study
Epidemiology
Geriatrics
Masticatory muscles
Oral health
Journal
BMC geriatrics
ISSN: 1471-2318
Titre abrégé: BMC Geriatr
Pays: England
ID NLM: 100968548
Informations de publication
Date de publication:
20 10 2021
20 10 2021
Historique:
received:
25
04
2021
accepted:
07
10
2021
entrez:
21
10
2021
pubmed:
22
10
2021
medline:
28
10
2021
Statut:
epublish
Résumé
Generalized loss of skeletal muscle mass (SMM) may modulate or otherwise affect the loss of masseter muscle mass and be responsible for low masseter muscle performance and strength (i.e., low oral function). Moreover, dentition status can affect oral function independent of the muscle state. This cross-sectional study aimed to simultaneously investigate the relationships among whole-body SMM, masseter muscle mass, oral function (masseter muscle performance and strength), and dentition status in 1349 Japanese adults (mean age = 73.6 years). We determined the estimated masseter muscle mass (e-MMM) based on morphological measurements of the masseter muscle. Masseter muscle performance was assessed via masticatory performance evaluation scores using gum, and strength was assessed as the maximal occlusal force. Dentition status was assessed as the number of functional teeth. SMM was measured by bioelectrical impedance analysis. Structural equation modeling stratified by sex was employed to investigate associations among SMM, e-MMM, gum score, occlusal force, and number of functional teeth. The direct path from SMM to e-MMM was statistically significant, as was the direct path from e-MMM to oral function (gum score and maximum occlusal force) for both sexes. We additionally confirmed that SMM indirectly affected gum score and maximum occlusal force via e-MMM (men; standardized coefficient [95% CI] = 3.64 [1.31 to 5.96] for maximum occlusal force and 0.01 [0.01 to 0.02] for gum score, women; 2.01 [0.38 to 3.81] for maximum occlusal force and 0.01 [0.002 to 0.01] for gum score). The number of functional teeth had direct effects on e-MMM, gum score, and maximum occlusal force. Low SMM was significantly indirectly associated with poor oral function through a low masseter muscle mass, and dentition status was independently associated with oral function.
Sections du résumé
BACKGROUND
Generalized loss of skeletal muscle mass (SMM) may modulate or otherwise affect the loss of masseter muscle mass and be responsible for low masseter muscle performance and strength (i.e., low oral function). Moreover, dentition status can affect oral function independent of the muscle state. This cross-sectional study aimed to simultaneously investigate the relationships among whole-body SMM, masseter muscle mass, oral function (masseter muscle performance and strength), and dentition status in 1349 Japanese adults (mean age = 73.6 years).
METHODS
We determined the estimated masseter muscle mass (e-MMM) based on morphological measurements of the masseter muscle. Masseter muscle performance was assessed via masticatory performance evaluation scores using gum, and strength was assessed as the maximal occlusal force. Dentition status was assessed as the number of functional teeth. SMM was measured by bioelectrical impedance analysis. Structural equation modeling stratified by sex was employed to investigate associations among SMM, e-MMM, gum score, occlusal force, and number of functional teeth.
RESULTS
The direct path from SMM to e-MMM was statistically significant, as was the direct path from e-MMM to oral function (gum score and maximum occlusal force) for both sexes. We additionally confirmed that SMM indirectly affected gum score and maximum occlusal force via e-MMM (men; standardized coefficient [95% CI] = 3.64 [1.31 to 5.96] for maximum occlusal force and 0.01 [0.01 to 0.02] for gum score, women; 2.01 [0.38 to 3.81] for maximum occlusal force and 0.01 [0.002 to 0.01] for gum score). The number of functional teeth had direct effects on e-MMM, gum score, and maximum occlusal force.
CONCLUSIONS
Low SMM was significantly indirectly associated with poor oral function through a low masseter muscle mass, and dentition status was independently associated with oral function.
Identifiants
pubmed: 34670508
doi: 10.1186/s12877-021-02552-9
pii: 10.1186/s12877-021-02552-9
pmc: PMC8529791
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
582Informations de copyright
© 2021. The Author(s).
Références
J Am Geriatr Soc. 2020 May;68(5):959-966
pubmed: 32162690
Nihon Koshu Eisei Zasshi. 2013 Sep;60(9):596-605
pubmed: 24125819
J Oral Rehabil. 2016 Jul;43(7):534-42
pubmed: 26854877
J Am Geriatr Soc. 2017 Jan;65(1):66-76
pubmed: 27655106
J Dent Res. 1999 Jan;78(1):31-42
pubmed: 10065943
J Geriatr Psychiatry Neurol. 2013 Dec;26(4):209-20
pubmed: 23920040
Gerodontology. 2017 Sep;34(3):357-364
pubmed: 28556346
Gerodontology. 2012 Jun;29(2):106-10
pubmed: 22356168
J Prosthodont Res. 2010 Jan;54(1):24-8
pubmed: 19837023
J Am Geriatr Soc. 2002 May;50(5):889-96
pubmed: 12028177
Proc Natl Sci Counc Repub China B. 2001 Jan;25(1):45-9
pubmed: 11254172
Geriatr Gerontol Int. 2015 Aug;15(8):1007-12
pubmed: 25363233
J Gerontol A Biol Sci Med Sci. 2006 Oct;61(10):1059-64
pubmed: 17077199
Geriatr Gerontol Int. 2015 Oct;15(10):1185-92
pubmed: 26272767
J Nutr Health Aging. 2020;24(9):1003-1010
pubmed: 33155629
J Nutr Health Aging. 2008 Aug-Sep;12(7):433-50
pubmed: 18615225
Arch Gerontol Geriatr. 2019 May - Jun;82:128-132
pubmed: 30780049
Eur J Orthod. 2007 Apr;29(2):149-56
pubmed: 17317862
J Frailty Aging. 2014;3(2):97-103
pubmed: 27049901
Community Dent Oral Epidemiol. 2014 Oct;42(5):441-50
pubmed: 25353039
Sci Rep. 2018 Mar 7;8(1):4104
pubmed: 29515146
PLoS One. 2014 Jun 12;9(6):e99487
pubmed: 24923425
Crit Rev Oral Biol Med. 2002;13(3):291-300
pubmed: 12090466
Gerodontology. 2020 Dec;37(4):383-388
pubmed: 32662134
J Dent Sci. 2021 Jan;16(1):380-388
pubmed: 33384824
Geriatr Gerontol Int. 2013 Apr;13(2):372-7
pubmed: 22805745
Int J Prosthodont. 1997 Jul-Aug;10(4):386-91
pubmed: 9484050
Geriatr Gerontol Int. 2020 Jun;20(6):607-614
pubmed: 32227400
Arch Oral Biol. 2011 Oct;56(10):991-6
pubmed: 21529776
Eur J Cardiovasc Prev Rehabil. 2008 Feb;15(1):104-6
pubmed: 18277194
J Oral Rehabil. 2016 Aug;43(8):565-74
pubmed: 27084614
J Oral Rehabil. 2020 Sep;47(9):1103-1109
pubmed: 32589302
BMC Geriatr. 2018 Mar 8;18(1):67
pubmed: 29519234
J Orofac Pain. 1997 Spring;11(2):101-14
pubmed: 10332316
J Cachexia Sarcopenia Muscle. 2014 Dec;5(4):269-77
pubmed: 25223471
Nutrition. 2019 May;61:111-118
pubmed: 30710883
Psychometrika. 2017 Jun;82(2):407-426
pubmed: 28447310
PLoS One. 2013 Jun 05;8(6):e64113
pubmed: 23755114
Arch Gerontol Geriatr. 2018 Sep - Oct;78:18-22
pubmed: 29883805