Oral Pemphigus Vulgaris.

bullae desmoglein mycophenolate mofetil pemphigus vulgaris triamcinolone acetonide tzanck test

Journal

Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737

Informations de publication

Date de publication:
Sep 2021
Historique:
accepted: 15 09 2021
entrez: 21 10 2021
pubmed: 22 10 2021
medline: 22 10 2021
Statut: epublish

Résumé

Pemphigus is a chronic mucocutaneous autoimmune disease with the clinical feature of blisters that initially appear in the oral cavity and later in the skin. The dental professionals play an important role in diagnosing the disease. Early diagnosis and treatment determine the course and prognosis of the disease. Systemic corticosteroids continue to be the standard therapy for pemphigus vulgaris (PV). Management of PV involves prolonged use of steroids to control the disease and prevent relapses, but associated adverse events constantly remain a great challenge. Regular periodic clinical evaluation of patients with pemphigus on steroids is mandatory. This article describes a case of a 50-year-old woman with multiple chronic ulcers in the oral cavity in whom the diagnosis of PV was made and treated. The case study is followed by a review of the literature including etiology, pathogenesis, clinical features, as well as the various diagnostic criteria and the therapeutic options of PV.

Identifiants

pubmed: 34671517
doi: 10.7759/cureus.18005
pmc: PMC8521543
doi:

Types de publication

Case Reports

Langues

eng

Pagination

e18005

Informations de copyright

Copyright © 2021, Subadra et al.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

Références

J Dtsch Dermatol Ges. 2011 Nov;9(11):927-47
pubmed: 22026362
Lancet. 2005 Jul 2-8;366(9479):61-73
pubmed: 15993235
J Eur Acad Dermatol Venereol. 2015 Mar;29(3):405-14
pubmed: 25338479
Clin Dermatol. 2005 May-Jun;23(3):223-6
pubmed: 15896536
Oral Dis. 2005 May;11(3):119-30
pubmed: 15888101
J Allergy Clin Immunol. 2003 Jan;111(1):3-22; quiz 23
pubmed: 12532089
Clin Cosmet Investig Dermatol. 2015 Oct 21;8:521-7
pubmed: 26543381
Bratisl Lek Listy. 2017;118(4):243-249
pubmed: 28471236
Allergy Asthma Clin Immunol. 2013 Aug 15;9(1):30
pubmed: 23947590
Int J Paediatr Dent. 2005 Jul;15(4):287-93
pubmed: 16011788
Br J Oral Maxillofac Surg. 2008 Jun;46(4):272-7
pubmed: 17870218
Indian J Dermatol Venereol Leprol. 2011 Nov-Dec;77(6):677-82
pubmed: 22016274
J Oral Sci. 2008 Sep;50(3):359-62
pubmed: 18818476
Arch Dermatol Res. 2003 Apr;295 Suppl 1:S2-11
pubmed: 12677426
J Clin Diagn Res. 2013 Dec;7(12):2788-92
pubmed: 24551638
J Periodontol. 2008 Dec;79(12):2241-6
pubmed: 19053912
J Dtsch Dermatol Ges. 2010 Aug;8(8):598-606
pubmed: 20180886
Int J Mol Sci. 2017 Nov 26;18(12):
pubmed: 29186863
Med Oral Patol Oral Cir Bucal. 2008 Oct 01;13(10):E622-6
pubmed: 18830168
Cell. 1991 Nov 29;67(5):869-77
pubmed: 1720352
J Am Acad Dermatol. 2013 Oct;69(4):583-8
pubmed: 23850258
Int J Periodontics Restorative Dent. 2001 Feb;21(1):85-90
pubmed: 11829040
J Am Acad Dermatol. 1987 Sep;17(3):437-42
pubmed: 3655023
Int J Dermatol. 1990 Jun;29(5):363-7
pubmed: 2361795
J Autoimmun. 2005 Jun;24(4):319-28
pubmed: 15869862

Auteurs

K Subadra (K)

Oral Medicine and Radiology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.

Sathasivasubramanian S (S)

Oral Medicine and Radiology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.

Aravind Warrier S (A)

Oral Medicine and Radiology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.

Classifications MeSH