Dementia in the older population is associated with neocortex content of serum amyloid P component.
dementia
neocortex
serum amyloid P component
Journal
Brain communications
ISSN: 2632-1297
Titre abrégé: Brain Commun
Pays: England
ID NLM: 101755125
Informations de publication
Date de publication:
2021
2021
Historique:
received:
31
05
2021
revised:
10
07
2021
accepted:
15
07
2021
entrez:
21
10
2021
pubmed:
22
10
2021
medline:
22
10
2021
Statut:
epublish
Résumé
Despite many reported associations, the direct cause of neurodegeneration responsible for cognitive loss in Alzheimer's disease and some other common dementias is not known. The normal human plasma protein, serum amyloid P component, a constituent of all human fibrillar amyloid deposits and present on most neurofibrillary tangles, is cytotoxic for cerebral neurones
Identifiants
pubmed: 34671726
doi: 10.1093/braincomms/fcab225
pii: fcab225
pmc: PMC8523881
doi:
Types de publication
Journal Article
Langues
eng
Pagination
fcab225Subventions
Organisme : Medical Research Council
ID : G0601022
Pays : United Kingdom
Organisme : Medical Research Council
ID : G9901400
Pays : United Kingdom
Informations de copyright
© The Author(s) (2021). Published by Oxford University Press on behalf of the Guarantors of Brain.
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