Microfluidic Lab-on-a-Chip Based on UHF-Dielectrophoresis for Stemness Phenotype Characterization and Discrimination among Glioblastoma Cells.

cancer stem cells glioblastoma cells high-frequency dielectrophoresis microfluidic point-of-care device single cell manipulation

Journal

Biosensors
ISSN: 2079-6374
Titre abrégé: Biosensors (Basel)
Pays: Switzerland
ID NLM: 101609191

Informations de publication

Date de publication:
13 Oct 2021
Historique:
received: 15 09 2021
revised: 08 10 2021
accepted: 12 10 2021
entrez: 22 10 2021
pubmed: 23 10 2021
medline: 6 1 2022
Statut: epublish

Résumé

Glioblastoma (GBM) is one of the most aggressive solid tumors, particularly due to the presence of cancer stem cells (CSCs). Nowadays, the characterization of this cell type with an efficient, fast and low-cost method remains an issue. Hence, we have developed a microfluidic lab-on-a-chip based on dielectrophoresis (DEP) single cell electro-manipulation to measure the two crossover frequencies:

Identifiants

pubmed: 34677344
pii: bios11100388
doi: 10.3390/bios11100388
pmc: PMC8534203
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : European Union
ID : 737164

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Auteurs

Elisa Lambert (E)

XLIM-UMR 7252, University of Limoges/CNRS, 87060 Limoges, France.

Rémi Manczak (R)

XLIM-UMR 7252, University of Limoges/CNRS, 87060 Limoges, France.

Elodie Barthout (E)

CAPTuR-EA 3842, University of Limoges, 87025 Limoges, France.

Sofiane Saada (S)

CAPTuR-EA 3842, University of Limoges, 87025 Limoges, France.

Elena Porcù (E)

Department of Women's and Children's Health (DSB), University of Padova, 35128 Padova, Italy.
Institute of Pediatric Research (IRP), 35127 Padova, Italy.

Francesca Maule (F)

Arnie Charbonneau Cancer Institute, Department of Biochemistry and Molecular Biology, University of Calgary, Calgary, AB T2N 1N4, Canada.

Barbara Bessette (B)

CAPTuR-EA 3842, University of Limoges, 87025 Limoges, France.

Giampietro Viola (G)

Department of Women's and Children's Health (DSB), University of Padova, 35128 Padova, Italy.
Institute of Pediatric Research (IRP), 35127 Padova, Italy.

Luca Persano (L)

Department of Women's and Children's Health (DSB), University of Padova, 35128 Padova, Italy.
Institute of Pediatric Research (IRP), 35127 Padova, Italy.

Claire Dalmay (C)

XLIM-UMR 7252, University of Limoges/CNRS, 87060 Limoges, France.

Fabrice Lalloué (F)

CAPTuR-EA 3842, University of Limoges, 87025 Limoges, France.

Arnaud Pothier (A)

XLIM-UMR 7252, University of Limoges/CNRS, 87060 Limoges, France.

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Classifications MeSH