CDKN2A
familial pancreatic cancer
induced pluripotent stem cells
pancreatic organoids
Journal
Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829
Informations de publication
Date de publication:
13 Oct 2021
13 Oct 2021
Historique:
received:
16
06
2021
revised:
05
10
2021
accepted:
09
10
2021
entrez:
23
10
2021
pubmed:
24
10
2021
medline:
24
10
2021
Statut:
epublish
Résumé
Patient-derived induced pluripotent stem cells (iPSCs) provide a unique platform to study hereditary disorders and predisposition syndromes by resembling germline mutations of affected individuals and by their potential to differentiate into nearly every cell type of the human body. We employed plucked human hair from two siblings with a family history of cancer carrying a pathogenic
Identifiants
pubmed: 34680288
pii: cancers13205139
doi: 10.3390/cancers13205139
pmc: PMC8533699
pii:
doi:
Types de publication
Journal Article
Langues
eng
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