HMGA2 Supports Cancer Hallmarks in Triple-Negative Breast Cancer.

HMGA2 IL-6 IL-8 NF-kB STAT3 triple-negative breast cancer

Journal

Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829

Informations de publication

Date de publication:
16 Oct 2021
Historique:
received: 03 10 2021
accepted: 11 10 2021
entrez: 23 10 2021
pubmed: 24 10 2021
medline: 24 10 2021
Statut: epublish

Résumé

Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer that exhibits a high proliferation rate and early metastasis leading to a poor prognosis. HMGA2 is a DNA binding transcriptional regulator implicated in tumorigenesis. Here, we demonstrate that the

Identifiants

pubmed: 34680349
pii: cancers13205197
doi: 10.3390/cancers13205197
pmc: PMC8533747
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Behzad Mansoori (B)

Immunology Research Center, Tabriz University of Medical Sciences, Golghasht St., Tabriz 51666-14731, Iran.
Department of Cancer and Inflammation Research, Institute for Molecular Medicine, University of Southern Denmark, J. B. Winsløws Vej 25, 3, DK-5000 Odense C, Denmark.
Aging Research Institute, Physical Medicine and Rehabilitation Research Center, Tabriz University of Medical Sciences, Golghasht St., Tabriz 51656-65811, Iran.

Mikkel Green Terp (MG)

Department of Cancer and Inflammation Research, Institute for Molecular Medicine, University of Southern Denmark, J. B. Winsløws Vej 25, 3, DK-5000 Odense C, Denmark.

Ali Mohammadi (A)

Department of Cancer and Inflammation Research, Institute for Molecular Medicine, University of Southern Denmark, J. B. Winsløws Vej 25, 3, DK-5000 Odense C, Denmark.

Christina Bøg Pedersen (CB)

Department of Cancer and Inflammation Research, Institute for Molecular Medicine, University of Southern Denmark, J. B. Winsløws Vej 25, 3, DK-5000 Odense C, Denmark.

Henrik Jørn Ditzel (HJ)

Department of Cancer and Inflammation Research, Institute for Molecular Medicine, University of Southern Denmark, J. B. Winsløws Vej 25, 3, DK-5000 Odense C, Denmark.
Department of Oncology, Odense University Hospital, DK-5000 Odense C, Denmark.
Academy of Geriatric Cancer Research (AgeCare), Odense University Hospital, DK-5000 Odense C, Denmark.

Behzad Baradaran (B)

Immunology Research Center, Tabriz University of Medical Sciences, Golghasht St., Tabriz 51666-14731, Iran.

Morten Frier Gjerstorff (MF)

Department of Cancer and Inflammation Research, Institute for Molecular Medicine, University of Southern Denmark, J. B. Winsløws Vej 25, 3, DK-5000 Odense C, Denmark.
Department of Oncology, Odense University Hospital, DK-5000 Odense C, Denmark.
Academy of Geriatric Cancer Research (AgeCare), Odense University Hospital, DK-5000 Odense C, Denmark.

Classifications MeSH