Particulate Matter Exposure and Allergic Rhinitis: The Role of Plasmatic Extracellular Vesicles and Bacterial Nasal Microbiome.

allergic rhinitis bacterial nasal microbiome extracellular vesicles particulate matter exposure

Journal

International journal of environmental research and public health
ISSN: 1660-4601
Titre abrégé: Int J Environ Res Public Health
Pays: Switzerland
ID NLM: 101238455

Informations de publication

Date de publication:
12 10 2021
Historique:
received: 18 08 2021
revised: 04 10 2021
accepted: 06 10 2021
entrez: 23 10 2021
pubmed: 24 10 2021
medline: 3 11 2021
Statut: epublish

Résumé

Particulate matter (PM) exposure is linked to the worsening of respiratory conditions, including allergic rhinitis (AR), as it can trigger nasal and systemic inflammation. To unveil the underlying molecular mechanisms, we investigated the effects of PM exposure on the release of plasmatic extracellular vesicles (EV) and on the complex cross-talk between the host and the nasal microbiome. To this aim, we evaluated the effects of PM

Identifiants

pubmed: 34682436
pii: ijerph182010689
doi: 10.3390/ijerph182010689
pmc: PMC8535327
pii:
doi:

Substances chimiques

Particulate Matter 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Jacopo Mariani (J)

EPIGET LAB, Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.

Simona Iodice (S)

EPIGET LAB, Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.

Laura Cantone (L)

EPIGET LAB, Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.

Giulia Solazzo (G)

EPIGET LAB, Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.

Paolo Marraccini (P)

Department of Preventive Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.

Emanuele Conforti (E)

Department of Preventive Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.

Pallav A Bulsara (PA)

GlaxoSmithKline Consumer Healthcare, Warren, NJ 07059, USA.

Maria Stella Lombardi (MS)

GlaxoSmithKline Consumer Healthcare, CH-1260 Nyon, Switzerland.

Robert P Howlin (RP)

GlaxoSmithKline Consumer Healthcare, Weybridge KT13 0DE, UK.

Valentina Bollati (V)

EPIGET LAB, Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.

Luca Ferrari (L)

EPIGET LAB, Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.

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Classifications MeSH