Haemophilic Pelvic Pseudotumour: A New Surgical Option.
complication
haemophilia
pelvis
perioperative management
pseudotumour
surgical treatment
Journal
Healthcare (Basel, Switzerland)
ISSN: 2227-9032
Titre abrégé: Healthcare (Basel)
Pays: Switzerland
ID NLM: 101666525
Informations de publication
Date de publication:
26 Sep 2021
26 Sep 2021
Historique:
received:
08
08
2021
revised:
23
09
2021
accepted:
24
09
2021
entrez:
23
10
2021
pubmed:
24
10
2021
medline:
24
10
2021
Statut:
epublish
Résumé
Haemophilia is an inherited coagulopathy caused by the absence or dysfunction of clotting factor VIII or IX. Clinical manifestations are generally secondary to recurrent bleeding episodes mainly in the musculoskeletal system. Bleeding symptoms appear early in life and, when the disease is severe (when plasma factor VIII or IX activity is <1% of normal), joint and muscle bleeding may occur spontaneously. A pseudotumour is a recurrent, chronic, encapsulated, slowly expanding, muscle hematoma. Haemophilic pseudotumour is a rare complication of haemophilia which occurs, as a condition either from repeated spontaneous bleeding or coming from a traumatic origin, in 1-2% of haemophilic patients. A 32-year-old man with severe haemophilia A referred to our Clinic with a massive right iliac wing pseudotumour complicated by Staphylococcus aureus superinfection and skin fistulisation. In this report we describe the medical management and surgical treatment by the adoption of a novel surgical technique which involves the use of a pedicle-screw and rod system (PSRS), a polyglycolic acid MESH and bone cement in order to build up an artificial ilium-like bony mass. This case report highlights the importance of interdisciplinary approach and the efficacy of eradicating surgery as treatment, especially in the case of large and long-lasting lesions.
Sections du résumé
BACKGROUND
BACKGROUND
Haemophilia is an inherited coagulopathy caused by the absence or dysfunction of clotting factor VIII or IX. Clinical manifestations are generally secondary to recurrent bleeding episodes mainly in the musculoskeletal system. Bleeding symptoms appear early in life and, when the disease is severe (when plasma factor VIII or IX activity is <1% of normal), joint and muscle bleeding may occur spontaneously. A pseudotumour is a recurrent, chronic, encapsulated, slowly expanding, muscle hematoma. Haemophilic pseudotumour is a rare complication of haemophilia which occurs, as a condition either from repeated spontaneous bleeding or coming from a traumatic origin, in 1-2% of haemophilic patients.
CASE REPORT
METHODS
A 32-year-old man with severe haemophilia A referred to our Clinic with a massive right iliac wing pseudotumour complicated by Staphylococcus aureus superinfection and skin fistulisation. In this report we describe the medical management and surgical treatment by the adoption of a novel surgical technique which involves the use of a pedicle-screw and rod system (PSRS), a polyglycolic acid MESH and bone cement in order to build up an artificial ilium-like bony mass. This case report highlights the importance of interdisciplinary approach and the efficacy of eradicating surgery as treatment, especially in the case of large and long-lasting lesions.
Identifiants
pubmed: 34682949
pii: healthcare9101269
doi: 10.3390/healthcare9101269
pmc: PMC8536013
pii:
doi:
Types de publication
Case Reports
Langues
eng
Références
Medicine (Baltimore). 2019 Nov;98(46):e17998
pubmed: 31725667
Haemophilia. 2013 Jan;19(1):e1-47
pubmed: 22776238
J Orthop Surg Res. 2017 Dec 01;12(1):185
pubmed: 29191213
World J Surg Oncol. 2013 Jul 16;11:156
pubmed: 23866921
Anaesthesia. 2016 Jul;71(7):829-42
pubmed: 27062274
Am J Hematol. 1994 Feb;45(2):103-8
pubmed: 8141115
J Pediatr Hematol Oncol. 2004 Feb;26(2):128-32
pubmed: 14767206
J Bone Joint Surg Br. 1997 Jan;79(1):26-30
pubmed: 9020440
Pan Afr Med J. 2015 Oct 16;22:149
pubmed: 26889330
Radiographics. 2003 Jul-Aug;23(4):852-6
pubmed: 12853660
J Pediatr Hematol Oncol. 2008 Aug;30(8):605-7
pubmed: 18799938
Br J Neurosurg. 2009 Aug;23(4):455-7
pubmed: 19637022
J Orthop Surg Res. 2021 Apr 21;16(1):275
pubmed: 33882996
J Clin Orthop Trauma. 2013 Dec;4(4):157-63
pubmed: 26403875
Semin Thromb Hemost. 2016 Sep;42(6):689-92
pubmed: 27472424
Clin Orthop Relat Res. 2005 Sep;438:36-41
pubmed: 16131867
Haemophilia. 2006 Sep;12(5):541-4
pubmed: 16919086
J Pediatr Hematol Oncol. 2015 Apr;37(3):219-22
pubmed: 24942018
J Neurosurg. 1993 Dec;79(6):936-8
pubmed: 8246062
Contemp Oncol (Pozn). 2016;20(1):73-9
pubmed: 27095944
Arch Bone Jt Surg. 2019 Nov;7(6):514-522
pubmed: 31970256
Semin Musculoskelet Radiol. 2003 Jun;7(2):127-36
pubmed: 12920650
Neurosurgery. 1996 Dec;39(6):1239-42
pubmed: 8938781
Int Orthop. 2012 Oct;36(10):2157-62
pubmed: 22752668
Arch Bone Jt Surg. 2020 Mar;8(2):121-130
pubmed: 32490041
Haemophilia. 2015 Sep;21(5):681-5
pubmed: 25688657
Haemophilia. 2007 Mar;13(2):209-12
pubmed: 17286777
Haemophilia. 2015 Nov;21(6):e484-6
pubmed: 26179428
Haemophilia. 2021 Jul;27(4):e543-e546
pubmed: 33650756
Artif Cells Blood Substit Immobil Biotechnol. 2011 Apr;39(2):87-91
pubmed: 20626231
Oncotarget. 2017 Jun 13;8(24):38978-38989
pubmed: 28465495
Haemophilia. 2020 Jan;26(1):33-40
pubmed: 31742871
J Bone Joint Surg Br. 2007 Jul;89(7):851-7
pubmed: 17673574
Neurol Med Chir (Tokyo). 2012;52(10):745-7
pubmed: 23095268
J Blood Med. 2014 Oct 17;5:207-18
pubmed: 25378964
Clin Orthop Relat Res. 2013 Mar;471(3):947-55
pubmed: 23065355
Haemophilia. 2009 Mar;15(2):448-57
pubmed: 19175421
Blood Coagul Fibrinolysis. 2019 Sep;30(1S Suppl 1):S11-S13
pubmed: 31517710
J Perioper Pract. 2011 Sep;21(9):304-8
pubmed: 22474774
Acta Orthop Scand. 1984 Dec;55(6):597-600
pubmed: 6524324
J Int Med Res. 2018 Jan;46(1):368-380
pubmed: 28661263
Haemophilia. 2020 Sep;26(5):873-881
pubmed: 32700372
Bosn J Basic Med Sci. 2018 May 20;18(2):206-210
pubmed: 29236646