Left Ventricular Systolic Impairment after Pediatric Cardiac Surgery Assessed by STE Analysis.

cardiac surgery congenital heart disease echocardiography speckle tracking echocardiography

Journal

Healthcare (Basel, Switzerland)
ISSN: 2227-9032
Titre abrégé: Healthcare (Basel)
Pays: Switzerland
ID NLM: 101666525

Informations de publication

Date de publication:
09 Oct 2021
Historique:
received: 18 07 2021
revised: 27 09 2021
accepted: 05 10 2021
entrez: 23 10 2021
pubmed: 24 10 2021
medline: 24 10 2021
Statut: epublish

Résumé

Speckle-tracking echocardiography (STE) has gained increasing value in the evaluation of congenital heart diseases (CHD); however, its use in pediatric cardiac surgery is limited. To evaluate left ventricular (LV) systolic impairment after biventricular pediatric cardiac surgery by STE strain (ε) analysis. We prospectively enrolled 117 children undergoing cardiac surgery for CHD. Echocardiography was performed at four different times: pre-operatively, 12-36 h (Time 1), 3-5 days (Time 2), and 6-8 days (Time 3). Images were obtained in the 4-2-and 3 apical chamber's views to derive LV global and regional (basal/mid/apical) ε values. At different postoperative times, we performed 320 examinations in 117 children (mean age: 2.4 ± 3.9, range: 0-16 years); 117 age-matched healthy children served as controls. All global, basal, and mid LVε values decreased after surgery; the lowest values being at Time 1 ( STE ε analysis revealed a significant LV systolic impairment after surgery with amelioration thereafter but incomplete normalization at discharge. Base-apex differences emerged with apical segments that, contrary to all the other regions, showed relative hypercontractility after surgery. The slower recovery of LVε values compared to LVEF suggests that STE ε analysis may be more accurate for the follow-up of mild LV post-surgical impairment.

Sections du résumé

BACKGROUND BACKGROUND
Speckle-tracking echocardiography (STE) has gained increasing value in the evaluation of congenital heart diseases (CHD); however, its use in pediatric cardiac surgery is limited.
AIM OBJECTIVE
To evaluate left ventricular (LV) systolic impairment after biventricular pediatric cardiac surgery by STE strain (ε) analysis.
METHODS METHODS
We prospectively enrolled 117 children undergoing cardiac surgery for CHD. Echocardiography was performed at four different times: pre-operatively, 12-36 h (Time 1), 3-5 days (Time 2), and 6-8 days (Time 3). Images were obtained in the 4-2-and 3 apical chamber's views to derive LV global and regional (basal/mid/apical) ε values.
RESULTS RESULTS
At different postoperative times, we performed 320 examinations in 117 children (mean age: 2.4 ± 3.9, range: 0-16 years); 117 age-matched healthy children served as controls. All global, basal, and mid LVε values decreased after surgery; the lowest values being at Time 1 (
CONCLUSIONS CONCLUSIONS
STE ε analysis revealed a significant LV systolic impairment after surgery with amelioration thereafter but incomplete normalization at discharge. Base-apex differences emerged with apical segments that, contrary to all the other regions, showed relative hypercontractility after surgery. The slower recovery of LVε values compared to LVEF suggests that STE ε analysis may be more accurate for the follow-up of mild LV post-surgical impairment.

Identifiants

pubmed: 34683018
pii: healthcare9101338
doi: 10.3390/healthcare9101338
pmc: PMC8544436
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : NIGMS NIH HHS
ID : T32 GM136577
Pays : United States

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Auteurs

Massimiliano Cantinotti (M)

Fondazione G. Monasterio CNR-Regione Toscana, 54100 Massa, Italy.
Institute of Clinical Physiology, IFC, National Research Institute (CNR), 56121 Pisa, Italy.

Pietro Marchese (P)

Fondazione G. Monasterio CNR-Regione Toscana, 54100 Massa, Italy.
Department of Pediatrics, University of Pisa, 56121 Pisa, Italy.

Marco Scalese (M)

Institute of Clinical Physiology, IFC, National Research Institute (CNR), 56121 Pisa, Italy.

Paola Medino (P)

Fondazione G. Monasterio CNR-Regione Toscana, 54100 Massa, Italy.

Vivek Jani (V)

The Helen B. Taussig Heart Center, The Johns Hopkins Hospital and Johns Hopkins University, Baltimore, MD 21218, USA.

Eliana Franchi (E)

Fondazione G. Monasterio CNR-Regione Toscana, 54100 Massa, Italy.

Pak Vitali (P)

Fondazione G. Monasterio CNR-Regione Toscana, 54100 Massa, Italy.

Giuseppe Santoro (G)

Fondazione G. Monasterio CNR-Regione Toscana, 54100 Massa, Italy.

Cecilia Viacava (C)

Fondazione G. Monasterio CNR-Regione Toscana, 54100 Massa, Italy.

Nadia Assanta (N)

Fondazione G. Monasterio CNR-Regione Toscana, 54100 Massa, Italy.

Shelby Kutty (S)

The Helen B. Taussig Heart Center, The Johns Hopkins Hospital and Johns Hopkins University, Baltimore, MD 21218, USA.

Martin Koestenberger (M)

Department of Pediatrics, Division of Pediatric Cardiology, Medical University, 8036 Graz, Austria.

Raffaele Giordano (R)

Adult and Pediatric Cardiac Surgery Unit, Department of Advanced Biomedical Sciences, University of Naples Federico II, 80138 Naples, Italy.

Classifications MeSH