Non-Alcoholic Fatty Liver Disease and COVID-19-Two Pandemics Hitting at the Same Time.
COVID-19
liver injury
metabolic syndrome
metabolic-associated fatty liver disease
non-alcoholic fatty liver disease
Journal
Medicina (Kaunas, Lithuania)
ISSN: 1648-9144
Titre abrégé: Medicina (Kaunas)
Pays: Switzerland
ID NLM: 9425208
Informations de publication
Date de publication:
03 Oct 2021
03 Oct 2021
Historique:
received:
10
09
2021
revised:
29
09
2021
accepted:
01
10
2021
entrez:
23
10
2021
pubmed:
24
10
2021
medline:
27
10
2021
Statut:
epublish
Résumé
The COVID-19 pandemic was and still is a global burden with more than 178,000,000 cases reported so far. Although it mainly affects respiratory organs, COVID-19 has many extrapulmonary manifestations, including, among other things, liver injury. Many hypotheses have been proposed to explain direct and indirect impacts of the SARS-CoV-2 virus on the liver. Studies have shown that around 15-30% of patients with COVID-19 have underlying liver disease, and 20-35% of patients with COVID-19 had altered liver enzymes at admission. One of the hypotheses is reactivation of an underlying liver disease, such as non-alcoholic fatty liver disease (NAFLD). Some studies have shown that NAFLD is associated with severe COVID-19 and poor outcome; nevertheless, other studies showed no significant difference between groups in comparing complications and clinical outcomes. Patients with NAFLD may suffer severe COVID-19 due to other comorbidities, especially cardiovascular diseases. The link between NAFLD and COVID-19 is not clear yet, and further studies and research are needed.
Identifiants
pubmed: 34684094
pii: medicina57101057
doi: 10.3390/medicina57101057
pmc: PMC8540462
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Références
Lancet Respir Med. 2020 Apr;8(4):420-422
pubmed: 32085846
JAMA. 2020 Mar 17;323(11):1061-1069
pubmed: 32031570
Gastroenterology. 2020 May;158(7):1999-2014.e1
pubmed: 32044314
Gut. 2020 Jun;69(6):1141-1143
pubmed: 32102928
Dig Liver Dis. 2021 Feb;53(2):153-157
pubmed: 33011088
J Virol. 2005 Dec;79(23):14614-21
pubmed: 16282461
Biochem Biophys Res Commun. 2020 May 21;526(1):135-140
pubmed: 32199615
Front Med (Lausanne). 2020 Jul 22;7:431
pubmed: 32793616
Influenza Other Respir Viruses. 2019 Jan;13(1):3-9
pubmed: 30515985
Eur J Clin Invest. 2020 Oct;50(10):e13338
pubmed: 32589264
J Med Virol. 2021 Jan;93(1):257-261
pubmed: 32603481
Lancet Respir Med. 2020 May;8(5):475-481
pubmed: 32105632
World J Gastroenterol. 2016 Nov 21;22(43):9488-9505
pubmed: 27920470
Lancet Gastroenterol Hepatol. 2020 May;5(5):428-430
pubmed: 32145190
Hepatol Res. 2020 Nov;50(11):1211-1221
pubmed: 32761993
J Hepatol. 2020 Aug;73(2):451-453
pubmed: 32278005
J Clin Transl Hepatol. 2020 Jun 28;8(2):0024
pubmed: 32309152
Gut Liver. 2021 Mar 15;15(2):206-216
pubmed: 32921636
Hepatol Int. 2009 Dec;3(4):526-36
pubmed: 19941170
N Engl J Med. 2020 Apr 30;382(18):1708-1720
pubmed: 32109013
Lancet Gastroenterol Hepatol. 2020 Jun;5(6):529-530
pubmed: 32203680
JHEP Rep. 2019 Feb 23;1(1):30-43
pubmed: 32149275
Lancet. 2020 Mar 28;395(10229):1054-1062
pubmed: 32171076
Eur J Med Res. 2020 Dec 2;25(1):64
pubmed: 33267871
Arch Toxicol. 2020 Apr;94(4):1367-1369
pubmed: 32266419
Metabolism. 2020 Jul;108:154244
pubmed: 32320741
SN Compr Clin Med. 2020 Nov 6;:1-4
pubmed: 33173850
J Hepatol. 2020 Sep;73(3):719-721
pubmed: 32348790
Lancet Microbe. 2020 Oct;1(6):e245-e253
pubmed: 32844161
Gut. 2020 Aug;69(8):1545-1547
pubmed: 32414813
J Hepatol. 2015 Apr;62(1 Suppl):S47-64
pubmed: 25920090
Liver Int. 2020 Oct;40(10):2515-2521
pubmed: 32585065
J Viral Hepat. 2021 Jan;28(1):89-94
pubmed: 32969557
Liver Int. 2020 Sep;40(9):2110-2116
pubmed: 32654359
Diabetes Metab Syndr. 2020 Jul - Aug;14(4):395-403
pubmed: 32334395
Trop Med Int Health. 2020 Mar;25(3):278-280
pubmed: 32052514
J Clin Transl Hepatol. 2020 Mar 28;8(1):13-17
pubmed: 32274341
J Hepatol. 2021 Feb;74(2):482-484
pubmed: 33223215
Biochimie. 2020 Dec;179:266-274
pubmed: 32891697
Nat Med. 2020 Jul;26(7):1017-1032
pubmed: 32651579
Front Med. 2020 Apr;14(2):185-192
pubmed: 32170560
Clin Liver Dis (Hoboken). 2020 May 07;15(4):162-167
pubmed: 32395244
J Clin Transl Hepatol. 2020 Mar 28;8(1):18-24
pubmed: 32274342
J Hepatol. 2020 Sep;73(3):717-718
pubmed: 32360995
Int J Cardiol. 2018 May 15;259:198-204
pubmed: 29579601
Nat Rev Gastroenterol Hepatol. 2017 Jan;14(1):55-66
pubmed: 27924081
Lancet. 2020 Feb 15;395(10223):507-513
pubmed: 32007143
Gastroenterology. 2020 Jul;159(1):373-375.e2
pubmed: 32294477
Obes Res Clin Pract. 2020 Jul - Aug;14(4):295-300
pubmed: 32660813
World J Clin Cases. 2020 Oct 6;8(19):4303-4310
pubmed: 33083389
Hepatol Commun. 2020 Aug 06;:
pubmed: 32838108