Increased Adiposity Appraised with CUN-BAE Is Highly Predictive of Incident Hypertension. The SUN Project.
CUN-BAE
adiposity
blood pressure
body fat
cohort studies
diet
hypertension
obesity
overweight
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
22 Sep 2021
22 Sep 2021
Historique:
received:
01
08
2021
revised:
28
08
2021
accepted:
18
09
2021
entrez:
23
10
2021
pubmed:
24
10
2021
medline:
20
11
2021
Statut:
epublish
Résumé
Overweight and obesity are growing worldwide and strongly associated with hypertension. The Clínica Universidad de Navarra-Body Adiposity Estimator (CUN-BAE) index is proposed as an optimal indicator of body fatness. We aimed to investigate the association of body fat as captured by the CUN-BAE index with incident hypertension in a Mediterranean population. We assessed 15,950 participants of the SUN (Seguimiento Universidad de Navarra) prospective cohort (63.7% women) initially free of hypertension. Participants completed follow-up questionnaires biennially. A validated 136-item food-frequency questionnaire was administered at baseline. We used Cox models adjusted for multiple confounders. Among 12.3 years of median follow-up (interquartile range: 8.3, 15.0 years), 2160 participants reported having received a diagnosis of hypertension. We observed a strong direct association between progressively higher the CUN-BAE index at baseline and incident hypertension during follow-up in multivariable-adjusted models for men and women, even after further adjustment for BMI ≥ 30 kg/m
Identifiants
pubmed: 34684310
pii: nu13103309
doi: 10.3390/nu13103309
pmc: PMC8537177
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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